LmjF.33.0960

nicotinate phosphoribosyltransferase, putative
Leishmania major strain Friedlin OG6: OG6_109462 OG7: OG7_0015320 164 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 164 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.35.4280 ⚠
Spindle assembly abnormal protein 6 homolog
— OG7
LmjF.25.1370
TAP42-like family, putative
— Both
LmjF.26.2370
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LmjF.12.0020
PITH domain-containing protein
— Both
LmjF.21.0500
hypothetical protein, conserved
— Both
LmjF.35.0030
pyruvate kinase
— Both
LmjF.35.4470 ⚠
Co-chaperone protein P23
— Both
LmjF.36.0890
eukaryotic translation initiation factor 6 (e
— Both
LmjF.20.0600 ⚠
hypothetical protein, conserved
— Both
LmjF.18.0990
UDP-glucose pyrophosphorylase
— Both
LmjF.34.2000
pyroglutamyl-peptidase I (C15 family)
— Both
LmjF.18.0210
Activator of Hsp90 ATPase, N-terminal/Activat
— Both
LmjF.16.0580
dihydroorotase, putative
— Both
LmjF.26.2700
6-phosphogluconolactonase
— Both
LmjF.21.0040 ⚠
hypothetical protein, conserved
— Both
LmjF.10.0200
Mitogen-activated protein kinase 10, putative
— OG6
LmjF.33.0090
hypothetical protein, conserved
— Both
LmjF.31.1070
biotin/lipoate protein ligase-like protein
— Both
LmjF.25.2010
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— Both
LmjF.25.1290
NPL4 family, putative
— Both
LmjF.36.6180 ⚠
Sucrase/ferredoxin-like, putative
— Both
LmjF.28.0060
hypothetical protein, conserved
— Both
LmjF.33.2810 ⚠
transcription elongation factor-like protein
— Both
LmjF.01.0220
cyclophilin 12, putative
— OG6
LmjF.23.1400
Ran-binding protein, putative
— Both
LmjF.34.0540
Gamma-soluble NSF attachment protein (SNAP-ga
— Both
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmjF.31.0290 ⚠
Kinesin-13 4, putative
— OG7
LmjF.13.1610 ⚠
Kinesin-13 5, putative
— OG7
LmjF.01.0030 ⚠
Kinesin-13 1, putative
— OG7
LmjF.13.0130 ⚠
Kinesin-13 2
— OG7
LmjF.08.0870
hypothetical protein, unknown function
— OG7
LmjF.27.2410 ⚠
aldo-keto reductase-like protein
— OG7
LmjF.31.2880 ⚠
aldehyde reductase, putative
— OG7
LmjF.32.3110 ⚠
Serine hydrolase (FSH1)/50S ribosome-binding
— OG7
LmjF.27.1830 ⚠
GTP binding protein, putative
— OG7
LmjF.34.3970 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
LmjF.07.0050 ⚠
alpha-adaptin-like protein
— OG7
LmjF.25.1020 ⚠
dehydrogenase-like protein
— OG7
LmjF.05.1225
hypothetical protein
— OG7
LmjF.29.2020 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LmjF.14.1170 ⚠
ras-like small GTPases, putative
— OG7
LmjF.35.4260 ⚠
predicted zinc finger protein
— OG7
LmjF.35.3500 ⚠
zinc finger protein, putative
— OG7
LmjF.28.2000 ⚠
protein lipid droplet kinase (LDK)
— OG7
LmjF.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmjF.28.1960 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LmjF.30.0450 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LmjF.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.