LmjF.34.3970

AP-1 adapter complex gamma subunit, putative
Leishmania major strain Friedlin OG6: OG6_101228 OG7: OG7_0002298 119 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 119 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.03.0760 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.0090 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmjF.22.0310 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG7
LmjF.28.1960 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LmjF.31.1070 ⚠
biotin/lipoate protein ligase-like protein
— OG7
LmjF.25.2010 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG7
LmjF.25.1290 ⚠
NPL4 family, putative
— OG7
LmjF.32.2450 ⚠
Cid1 family poly A polymerase, putative
— OG7
LmjF.32.2070 ⚠
phosphopantetheine adenylyltransferase, putat
— OG7
LmjF.33.0730 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.29.2020 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LmjF.07.0900 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
LmjF.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmjF.28.2000 ⚠
protein lipid droplet kinase (LDK)
— OG7
LmjF.32.0080 ⚠
N-myristoyl transferase, putative
— OG7
LmjF.03.0570 ⚠
quinone oxidoreductase, putative
— OG7
LmjF.34.3780 ⚠
phosphomannomutase-like protein
— OG7
LmjF.32.0960 ⚠
ubiquitin-conjugating enzyme protein, putativ
— OG7
LmjF.22.0810 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
LmjF.29.0780 ⚠
U-box domain protein, putative
— OG7
LmjF.13.0730 ⚠
ubiquitin-like protein
— OG7
LmjF.32.3680 ⚠
3-hydroxyisobutyryl-coenzyme A hydrolase, put
— OG7
LmjF.34.0210 ⚠
CS domain containing protein, putative
— OG7
LmjF.19.1480 ⚠
eukaryotic translation initiation factor-like
— OG7
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG7
LmjF.33.1710 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
LmjF.29.0340 ⚠
UBX domain-containing protein
— OG7
LmjF.32.1580 ⚠
phosphomannose isomerase
— OG7
LmjF.16.1490 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.1110 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.33.2810 ⚠
transcription elongation factor-like protein
— OG7
LmjF.24.0210 ⚠
transcription elongation factor, putative
— OG7
LmjF.35.0820 ⚠
aspartate aminotransferase, putative
— OG7
LmjF.24.0370 ⚠
aspartate aminotransferase, putative
— OG7
LmjF.31.1610 ⚠
diphthine synthase-like protein
— OG7
LmjF.26.0320 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
LmjF.31.2810 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
LmjF.01.0210 ⚠
CUE domain/Domain of unknown function (DUF177
— OG7
LmjF.16.1340 ⚠
hypothetical protein, conserved
— OG7
LmjF.29.2100 ⚠
Present in the outer mitochondrial membrane p
— OG7
LmjF.30.0930 ⚠
conserved hypothetical protein, putative
— OG7
LmjF.28.2070 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
LmjF.22.0110 ⚠
GMP synthase [glutamine-hydrolysing]
— OG7
LmjF.25.1020 ⚠
dehydrogenase-like protein
— OG7
LmjF.28.1340 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LmjF.28.1370 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LmjF.16.0760 ⚠
transaldolase, putative
— OG7
LmjF.31.0140 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.