LmjF.28.1370

haloacid dehalogenase-like hydrolase, putative
Leishmania major strain Friedlin OG6: OG6_121196 OG7: OG7_0005628 182 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 182 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.12.0020 ⚠
PITH domain-containing protein
— +1 more Both
LmjF.28.1590 ⚠
Galactose oxidase, central domain containing
— OG7
LmjF.21.0040 ⚠
hypothetical protein, conserved
— Both
LmjF.36.6650 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
LmjF.32.0910 ⚠
Alpha/beta hydrolase family, putative
— Both
LmjF.31.0570
amino acid transporter aATP11, putative
— OG6
LmjF.10.0200
Mitogen-activated protein kinase 10, putative
— OG6
LmjF.33.0090 ⚠
hypothetical protein, conserved
— Both
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmjF.28.2070 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
LmjF.31.1070 ⚠
biotin/lipoate protein ligase-like protein
— Both
LmjF.25.2010 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— Both
LmjF.25.1290 ⚠
NPL4 family, putative
— Both
LmjF.36.2950 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— Both
LmjF.35.0820 ⚠
aspartate aminotransferase, putative
— Both
LmjF.08.0340 ⚠
hypothetical protein, conserved
— Both
LmjF.28.1110 ⚠
WD domain, G-beta repeat, putative
— Both
LmjF.28.1140 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LmjF.23.1480 ⚠
alanine racemase, putative
— Both
LmjF.22.0320 ⚠
SEP domain containing protein, putative
— Both
LmjF.04.0070 ⚠
hypothetical protein, conserved
— Both
LmjF.33.2810 ⚠
transcription elongation factor-like protein
— Both
LmjF.06.1070 ⚠
deoxyribose-phosphate aldolase, putative
— Both
LmjF.31.0290 ⚠
Kinesin-13 4, putative
— OG7
LmjF.13.1610 ⚠
Kinesin-13 5, putative
— OG7
LmjF.01.0030 ⚠
Kinesin-13 1, putative
— OG7
LmjF.13.0130 ⚠
Kinesin-13 2
— OG7
LmjF.08.0870 ⚠
hypothetical protein, unknown function
— OG7
LmjF.27.2410 ⚠
aldo-keto reductase-like protein
— OG7
LmjF.31.2880 ⚠
aldehyde reductase, putative
— OG7
LmjF.05.1100 ⚠
methyltransferase domain containing protein,
— OG7
LmjF.34.3970 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
LmjF.36.0540 ⚠
ubiquitin-like protein, putative
— OG7
LmjF.32.3660 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmjF.26.1570 ⚠
thimet oligopeptidase, putative
— OG7
LmjF.21.0150 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
LmjF.06.0510 ⚠
U-box domain containing protein, putative
— OG7
LmjF.21.0030 ⚠
hypothetical protein, conserved
— OG7
LmjF.21.1740 ⚠
RNA polymerase II, putative
— OG7
LmjF.19.1500 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
LmjF.17.1390 ⚠
myo-inositol-1(or 4)-monophosphatase 1, putat
— OG7
LmjF.36.0900 ⚠
SNF1-related protein kinases, putative
— OG7
LmjF.32.3670 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmjF.30.3410 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.3650 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmjF.28.2150 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.1030 ⚠
hypothetical protein, conserved
— OG7
LmjF.07.0030 ⚠
hypothetical protein, conserved
— OG7
LmjF.17.1150 ⚠
5'-3' exoribonuclease B, putative
— OG7
LmjF.34.1260 ⚠
mitochondrial DNA polymerase I protein A, put
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.