LmjF.05.1100

methyltransferase domain containing protein, putative
Leishmania major strain Friedlin OG6: OG6_100611 OG7: OG7_0003453 42 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 42 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.31.2070 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LmjF.34.1260 ⚠
mitochondrial DNA polymerase I protein A, put
— OG7
LmjF.28.1340 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LmjF.35.2410 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.28.1350 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.16.1480 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.2910 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.24.0890 ⚠
DNA polymerase theta
— OG7
LmjF.28.1360 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.36.3430 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LmjF.28.1380 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.30.1680 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LmjF.31.1650 ⚠
MYND finger, putative
— OG7
LmjF.32.1260 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LmjF.31.2060 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LmjF.30.0890 ⚠
adenosine kinase-like protein
— OG7
LmjF.32.1270 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LmjF.25.1020 ⚠
dehydrogenase-like protein
— OG7
LmjF.31.2050 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LmjF.35.3560 ⚠
CRAL/TRIO, N-terminal domain/CRAL/TRIO domain
— OG7
LmjF.34.2000 ⚠
pyroglutamyl-peptidase I (C15 family)
— Both
LmjF.03.0980 ⚠
eukaryotic translation initiation factor 2 su
— Both
LmjF.30.0880 ⚠
adenosine kinase, putative
— Both
LmjF.34.3600 ⚠
adenosine kinase-like protein
— Both
LmjF.28.0510 ⚠
hypothetical protein, conserved
— Both
LmjF.30.0180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
LmjF.20.0660 ⚠
serine/threonine protein phosphatase 2A regul
— Both
LmjF.26.1910 ⚠
deoxyhypusine hydroxylase, putative
— Both
LmjF.09.0600 ⚠
cyclin 1
— Both
LmjF.36.6760 ⚠
ATP synthase delta (OSCP) subunit, putative
— Both
LmjF.36.3540
Domain of unknown function (DUF3846)/TPR repe
— OG6
LmjF.21.0640 ⚠
phosphoglucomutase, putative
— Both
LmjF.35.1250 ⚠
monothiol glutaredoxin, putative
— Both
LmjF.05.0310 ⚠
monothiol glutaredoxin, putative
— Both
LmjF.04.0070 ⚠
hypothetical protein, conserved
— Both
LmjF.16.1490 ⚠
hypothetical protein, conserved
— Both
LmjF.01.0110 ⚠
monothiol glutaredoxin, putative
— OG7
LmjF.28.1370 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LmjF.08.0340 ⚠
hypothetical protein, conserved
— OG7
LmjF.12.0190 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.12.0020 ⚠
PITH domain-containing protein
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.