LmjF.01.0110

monothiol glutaredoxin, putative
Leishmania major strain Friedlin OG6: OG6_101462 OG7: OG7_0003454 68 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 68 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.16.1490 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.3260 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.34.4280 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.18.0190 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LmjF.29.1350 ⚠
RNA binding protein, putative
— OG7
LmjF.33.0140 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.03.0480 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LmjF.35.2670 ⚠
ankyrin repeat protein, putative
— OG7
LmjF.29.1340 ⚠
RNA-binding protein, putative
— OG7
LmjF.29.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.18.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.34.2000 ⚠
pyroglutamyl-peptidase I (C15 family)
— OG7
LmjF.34.3780 ⚠
phosphomannomutase-like protein
— OG7
LmjF.32.2400 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.2150 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.3410 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.6640 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.4280 ⚠
Spindle assembly abnormal protein 6 homolog
— OG7
LmjF.32.1820 ⚠
iron superoxide dismutase, putative
— OG7
LmjF.36.3880 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LmjF.27.1250 ⚠
Serine-threonine kinase receptor-associated p
— OG7
LmjF.26.0320 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
LmjF.32.1100 ⚠
exportin 1, putative
— OG7
LmjF.31.0255 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.6180 ⚠
Sucrase/ferredoxin-like, putative
— OG7
LmjF.32.1830 ⚠
iron superoxide dismutase, putative
— OG7
LmjF.08.0290 ⚠
iron superoxide dismutase A, mitochondrial
— OG7
LmjF.34.0540 ⚠
Gamma-soluble NSF attachment protein (SNAP-ga
— OG7
LmjF.32.2630 ⚠
superoxide dismutase, putative
— OG7
LmjF.16.0040 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— OG7
LmjF.22.0110 ⚠
GMP synthase [glutamine-hydrolysing]
— OG7
LmjF.36.4500 ⚠
Protein of unknown function (DUF2870), putati
— OG7
LmjF.12.0020 ⚠
PITH domain-containing protein
— OG7
LmjF.33.0960 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
LmjF.25.0520 ⚠
RNA-binding protein, putative
— OG7
LmjF.22.1280 ⚠
hypothetical protein, unknown function
— Both
LmjF.21.0500 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.1155 ⚠
Uncharacterised ACR, YggU family COG1872, put
— Both
LmjF.09.1250
hypothetical protein, conserved
— OG6
LmjF.18.0170 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— Both
LmjF.18.0180 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— Both
LmjF.31.2570 ⚠
hypothetical protein, unknown function
— Both
LmjF.32.1840
rab11B GTPase, putative
— OG6
LmjF.29.1360 ⚠
RNA binding protein, putative
— OG6
LmjF.28.0060 ⚠
hypothetical protein, conserved
— OG7
LmjF.17.0360 ⚠
cytidine deaminase-like protein
— Both
LmjF.36.6465 ⚠
hypothetical protein, unknown function
— Both
LmjF.29.1370 ⚠
RNA binding protein, putative
— Both
LmjF.21.0790
ras-related protein Rab21, putative
— OG6
LmjF.36.1220 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.