LmjF.27.1250

Serine-threonine kinase receptor-associated protein, putative
Leishmania major strain Friedlin OG6: OG6_103369 OG7: OG7_0003947 69 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 69 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.28.2310 ⚠
Eukaryotic translation initiation factor 3 su
— OG7
LmjF.17.0010 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LmjF.36.6980 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LmjF.30.3040 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LmjF.36.0250 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LmjF.17.1290 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LmjF.36.6910 ⚠
T-complex protein 1, theta subunit, putative
— OG7
LmjF.27.1260 ⚠
T-complex protein 1, beta subunit, putative
— OG7
LmjF.32.1000 ⚠
chaperonin containing t-complex protein, puta
— OG7
LmjF.21.1090 ⚠
T-complex protein 1, delta subunit, putative
— OG7
LmjF.23.1220 ⚠
T-complex protein 1, gamma subunit, putative
— OG7
LmjF.33.2150 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.4280 ⚠
Spindle assembly abnormal protein 6 homolog
— OG7
LmjF.05.1225 ⚠
hypothetical protein
— OG7
LmjF.27.1830 ⚠
GTP binding protein, putative
— OG7
LmjF.32.3110 ⚠
Serine hydrolase (FSH1)/50S ribosome-binding
— OG7
LmjF.25.1060 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.2180 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LmjF.24.1210 ⚠
Eukaryotic translation initiation factor 1, p
— OG7
LmjF.18.0290 ⚠
dephospho-CoA kinase, putative
— OG7
LmjF.36.4500 ⚠
Protein of unknown function (DUF2870), putati
— Both
LmjF.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmjF.01.0110 ⚠
monothiol glutaredoxin, putative
— OG7
LmjF.14.1170 ⚠
ras-like small GTPases, putative
— OG7
LmjF.35.4260 ⚠
predicted zinc finger protein
— OG7
LmjF.35.3500 ⚠
zinc finger protein, putative
— OG7
LmjF.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmjF.32.2070 ⚠
phosphopantetheine adenylyltransferase, putat
— OG7
LmjF.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmjF.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmjF.19.1160 ⚠
hypothetical protein, conserved
— OG7
LmjF.31.0255 ⚠
hypothetical protein, conserved
— OG7
LmjF.25.1610 ⚠
Eukaryotic translation initiation factor 3 su
— OG7
LmjF.35.3860 ⚠
T-complex protein 1, eta subunit, putative
— OG7
LmjF.13.1660 ⚠
chaperonin TCP20, putative
— OG7
LmjF.32.3270 ⚠
chaperonin alpha subunit, putative
— OG7
LmjF.10.0490
mitogen-activated protein kinase 3, putative
— OG6
LmjF.12.0020 ⚠
PITH domain-containing protein
— Both
LmjF.08.0290 ⚠
iron superoxide dismutase A, mitochondrial
— Both
LmjF.20.0110 ⚠
phosphoglycerate kinase B, cytosolic
— Both
LmjF.23.0150
hypothetical protein, conserved
— OG6
LmjF.32.1820 ⚠
iron superoxide dismutase, putative
— Both
LmjF.32.2630 ⚠
superoxide dismutase, putative
— Both
LmjF.22.1530
dephospho-CoA kinase, putative
— OG6
LmjF.35.1250 ⚠
monothiol glutaredoxin, putative
— Both
LmjF.21.0500 ⚠
hypothetical protein, conserved
— Both
LmjF.10.0780 ⚠
WD domain, G-beta repeat, putative
— Both
LmjF.32.1830 ⚠
iron superoxide dismutase, putative
— Both
LmjF.05.0310 ⚠
monothiol glutaredoxin, putative
— Both
LmjF.20.0100 ⚠
phosphoglycerate kinase C, glycosomal
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.