LmjF.20.0100

phosphoglycerate kinase C, glycosomal
Leishmania major strain Friedlin OG6: OG6_100440 OG7: OG7_0003817 17 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 17 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.29.2570 ⚠
Serine/threonine-protein kinase NEK7, putativ
— OG6
LmjF.36.3880 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LmjF.34.3740 ⚠
serine palmitoyltransferase-like protein
— OG7
LmjF.35.0320 ⚠
serine palmitoyltransferase, putative
— OG7
LmjF.30.0380 ⚠
phosphatase 2C, putative
— OG6
LmjF.12.1140 ⚠
n-ethylmaleimide reductase-like protein
— Both
LmjF.12.1130 ⚠
Activating nitroreductase NTR2
— Both
LmjF.33.0830 ⚠
2,4-dienoyl-CoA reductase
— OG6
LmjF.25.0670 ⚠
epsin, putative
— Both
LmjF.32.1580 ⚠
phosphomannose isomerase
— Both
LmjF.10.0780 ⚠
WD domain, G-beta repeat, putative
— Both
LmjF.25.0710 ⚠
SCAMP family, putative
— Both
LmjF.34.2410 ⚠
Aminotransferase class IV, putative
— Both
LmjF.19.0150 ⚠
mitogen-activated protein kinase kinase kinas
— OG6
LmjF.27.1250 ⚠
Serine-threonine kinase receptor-associated p
— Both
LmjF.36.2950 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— Both
LmjF.26.0140 ⚠
adenine phosphoribosyltransferase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.