LmjF.08.0870

hypothetical protein, unknown function
Leishmania major strain Friedlin OG6: OG6_173730 OG7: OG7_0052186 116 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 116 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.28.1340 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LmjF.21.0040 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.0450 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LmjF.36.6650
2,3-bisphosphoglycerate-independent phosphogl
— OG7
LmjF.32.0910
Alpha/beta hydrolase family, putative
— OG7
LmjF.17.1150 ⚠
5'-3' exoribonuclease B, putative
— OG7
LmjF.16.1490
hypothetical protein, conserved
— OG7
LmjF.33.0090
hypothetical protein, conserved
— OG7
LmjF.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmjF.22.0310 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG7
LmjF.28.2070
tRNA threonylcarbamoyl adenosine modification
— OG7
LmjF.22.0320
SEP domain containing protein, putative
— OG7
LmjF.28.1960 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LmjF.31.1070
biotin/lipoate protein ligase-like protein
— OG7
LmjF.25.2010
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG7
LmjF.25.1290
NPL4 family, putative
— OG7
LmjF.13.0130 ⚠
Kinesin-13 2
— OG7
LmjF.07.0050 ⚠
alpha-adaptin-like protein
— OG7
LmjF.28.1140
electron-transfer-flavoprotein, alpha polypep
— OG7
LmjF.28.1110
WD domain, G-beta repeat, putative
— OG7
LmjF.32.2450 ⚠
Cid1 family poly A polymerase, putative
— OG7
LmjF.32.2070 ⚠
phosphopantetheine adenylyltransferase, putat
— OG7
LmjF.33.0730
WD domain, G-beta repeat, putative
— OG7
LmjF.36.1790 ⚠
5'-3' exoribonuclease D, putative
— OG7
LmjF.29.2020 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LmjF.07.0900 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
LmjF.25.1020 ⚠
dehydrogenase-like protein
— OG7
LmjF.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmjF.13.0730 ⚠
ubiquitin-like protein
— OG7
LmjF.16.0760
transaldolase, putative
— OG7
LmjF.31.2880 ⚠
aldehyde reductase, putative
— OG7
LmjF.26.0320
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
LmjF.31.0140
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.03.0760
hypothetical protein, conserved
— OG7
LmjF.28.1360 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.32.1580
phosphomannose isomerase
— OG7
LmjF.29.0340
UBX domain-containing protein
— OG7
LmjF.33.1710 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
LmjF.35.0820 ⚠
aspartate aminotransferase, putative
— OG7
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG7
LmjF.19.1480 ⚠
eukaryotic translation initiation factor-like
— OG7
LmjF.34.0210 ⚠
CS domain containing protein, putative
— OG7
LmjF.32.3680 ⚠
3-hydroxyisobutyryl-coenzyme A hydrolase, put
— OG7
LmjF.03.0570
quinone oxidoreductase, putative
— OG7
LmjF.31.1610
diphthine synthase-like protein
— OG7
LmjF.24.0640 ⚠
Kinesin-13 3, putative
— OG7
LmjF.28.1350 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.01.0210 ⚠
CUE domain/Domain of unknown function (DUF177
— OG7
LmjF.32.0080
N-myristoyl transferase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.