LmjF.24.0640

Kinesin-13 3, putative
Leishmania major strain Friedlin OG6: OG6_143225 OG7: OG7_0003411 167 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 167 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.23.1730 ⚠
RING-H2 zinc finger, putative
— Both
LmjF.17.0030 ⚠
Ring finger domain containing protein, putati
— OG7
LmjF.25.0340 ⚠
Ring finger domain containing protein, putati
— OG7
LmjF.36.2930 ⚠
predicted zinc finger protein
— OG7
LmjF.09.0350 ⚠
Ring finger domain containing protein, putati
— OG7
LmjF.27.1200 ⚠
RING-H2 zinc finger, putative
— OG7
LmjF.21.1295 ⚠
Ring finger domain containing protein, putati
— OG7
LmjF.36.0900 ⚠
SNF1-related protein kinases, putative
— OG7
LmjF.25.1290 ⚠
NPL4 family, putative
— Both
LmjF.28.1140 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LmjF.28.1110 ⚠
WD domain, G-beta repeat, putative
— Both
LmjF.06.1130 ⚠
hypothetical protein, conserved
— Both
LmjF.16.1340 ⚠
hypothetical protein, conserved
— Both
LmjF.22.0110 ⚠
GMP synthase [glutamine-hydrolysing]
— Both
LmjF.16.0310 ⚠
Met-10+ like-protein, putative
— Both
LmjF.16.0760 ⚠
transaldolase, putative
— Both
LmjF.23.0490 ⚠
5'-AMP-activated protein kinase subunit beta,
— Both
LmjF.33.1150 ⚠
pumilio protein 6, putative
— Both
LmjF.18.1420 ⚠
pumilio protein 2, putative
— Both
LmjF.20.0940 ⚠
cyclophilin 15, putative
— Both
LmjF.05.0610 ⚠
Surp module, putative
— Both
LmjF.18.0650 ⚠
PA26 p53-induced protein (sestrin), putative
— Both
LmjF.23.1480 ⚠
alanine racemase, putative
— Both
LmjF.22.0320 ⚠
SEP domain containing protein, putative
— Both
LmjF.33.2810 ⚠
transcription elongation factor-like protein
— Both
LmjF.18.0880
cyclosporin 16, putative
— OG6
LmjF.32.3980 ⚠
Gar1/Naf1 RNA binding region, putative
— Both
LmjF.32.1090 ⚠
HECT-domain (ubiquitin-transferase), putative
— Both
LmjF.33.1910 ⚠
ribosome assembly protein RRB1, putative
— Both
LmjF.26.1280 ⚠
hypothetical protein, conserved
— Both
LmjF.30.3360 ⚠
calmodulin-related protein, putative
— Both
LmjF.30.1550 ⚠
pseudouridine synthase A-like protein, putati
— Both
LmjF.32.2390 ⚠
hypothetical protein, conserved
— Both
LmjF.33.2980 ⚠
hypothetical protein, conserved
— Both
LmjF.35.2450 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.26.0420 ⚠
pseudouridylate synthase-like protein
— OG7
LmjF.34.3960 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.19.1020 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LmjF.36.4370 ⚠
ubiquitin protein ligase, putative
— OG7
LmjF.34.0310 ⚠
tRNA pseudouridine synthase, putative
— OG7
LmjF.26.2200 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.3970 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
LmjF.36.0540 ⚠
ubiquitin-like protein, putative
— OG7
LmjF.32.3660 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmjF.21.0150 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
LmjF.06.0510 ⚠
U-box domain containing protein, putative
— OG7
LmjF.28.0360 ⚠
ubiquitin activating enzyme, putative
— OG7
LmjF.28.1360 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.08.0870 ⚠
hypothetical protein, unknown function
— OG7
LmjF.33.1710 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.