LmjF.33.1910

ribosome assembly protein RRB1, putative
Leishmania major strain Friedlin OG6: OG6_102504 OG7: OG7_0007856 240 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 240 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.18.1210 ⚠
prolyl-tRNA synthetase, putative
— Both
LmjF.22.0650
guide RNA associated protein, GAP2, putative
— Both
LmjF.18.1220 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LmjF.18.0550
hypothetical protein, conserved
— Both
LmjF.01.0710 ⚠
ubiquitin activating enzyme, putative
— OG7
LmjF.08.0220 ⚠
ubiquitin-activating enzyme-like protein
— Both
LmjF.19.1020 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LmjF.26.0420 ⚠
pseudouridylate synthase-like protein
— OG7
LmjF.08.0410
WD domain, G-beta repeat, putative
— Both
LmjF.34.0310 ⚠
tRNA pseudouridine synthase, putative
— Both
LmjF.30.0560
hypothetical protein, conserved
— Both
LmjF.18.1320
hypothetical protein, conserved
— Both
LmjF.30.1550 ⚠
pseudouridine synthase A-like protein, putati
— Both
LmjF.20.1365 ⚠
pumillio protein 9, putative
— OG7
LmjF.34.1220 ⚠
inositol 5-phosphatase-like protein
— OG7
LmjF.15.0180 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.33.1830 ⚠
dual specificity tyrosine-phosphorylation-reg
— OG7
LmjF.33.1950 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.1860 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.34.3900 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.30.0730 ⚠
co-chaperone GrpE, putative
— OG7
LmjF.17.0030 ⚠
Ring finger domain containing protein, putati
— OG7
LmjF.25.0340 ⚠
Ring finger domain containing protein, putati
— OG7
LmjF.36.2930 ⚠
predicted zinc finger protein
— OG7
LmjF.09.0350 ⚠
Ring finger domain containing protein, putati
— OG7
LmjF.27.1200 ⚠
RING-H2 zinc finger, putative
— OG7
LmjF.21.1295 ⚠
Ring finger domain containing protein, putati
— OG7
LmjF.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmjF.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmjF.20.1090 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmjF.27.0550 ⚠
replication factor C, subunit 4, putative
— OG7
LmjF.20.1570 ⚠
amidohydrolase, putative
— Both
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmjF.24.2020
tubulin folding cofactor D, putative
— Both
LmjF.13.0940
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
LmjF.10.1200 ⚠
hypothetical protein, conserved
— Both
LmjF.26.1900 ⚠
hypothetical protein, conserved
— Both
LmjF.24.0640 ⚠
Kinesin-13 3, putative
— Both
LmjF.30.1380 ⚠
amidohydrolase, putative
— Both
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmjF.30.0735 ⚠
heat shock protein grpe
— Both
LmjF.23.1630 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.20.1550 ⚠
amidohydrolase, putative
— Both
LmjF.20.1560 ⚠
amidohydrolase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.