LmjF.01.0710

ubiquitin activating enzyme, putative
Leishmania major strain Friedlin OG6: OG6_101845 OG7: OG7_0003569 123 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 123 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG7
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG7
LmjF.08.0410 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.30.0560 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.1910 ⚠
ribosome assembly protein RRB1, putative
— OG7
LmjF.27.1340 ⚠
hypothetical protein, unknown function
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.22.0650 ⚠
guide RNA associated protein, GAP2, putative
— OG7
LmjF.26.1470 ⚠
farnesyltransferase beta subunit
— OG7
LmjF.36.4370 ⚠
ubiquitin protein ligase, putative
— OG7
LmjF.35.3200 ⚠
RNA-binding protein, putative
— OG7
LmjF.19.1050 ⚠
hypothetical protein, unknown function
— OG7
LmjF.18.1320 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.2260 ⚠
glycosyl hydrolase-like protein
— OG7
LmjF.35.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmjF.20.1090 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.1180 ⚠
hypothetical protein, conserved
— OG7
LmjF.11.0920 ⚠
Short C-terminal domain/PUB domain containing
— OG7
LmjF.35.4810 ⚠
BRCA1 C Terminus (BRCT) domain containing pro
— OG7
LmjF.21.0875 ⚠
hypothetical protein, conserved
— OG7
LmjF.11.0890 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.1090 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.18.1210 ⚠
prolyl-tRNA synthetase, putative
— OG7
LmjF.29.2490 ⚠
protein kinase, putative
— OG7
LmjF.25.1490 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
LmjF.23.1165 ⚠
coronin, putative
— OG7
LmjF.36.2420 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
LmjF.34.4290 ⚠
nucleolar protein family a, putative
— OG7
LmjF.24.1900 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG7
LmjF.12.0190 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.35.2410 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmjF.06.0940 ⚠
hypothetical protein, conserved
— OG7
LmjF.15.0280 ⚠
ribonucleoprotein p18, mitochondrial precurso
— OG7
LmjF.34.4090 ⚠
GRIP domain containing protein, putative
— OG7
LmjF.11.0990 ⚠
adaptin-related protein-like protein
— OG7
LmjF.36.5260 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
LmjF.36.6770 ⚠
beta adaptin, putative
— OG7
LmjF.35.1410 ⚠
threonyl-tRNA synthetase, putative
— OG7
LmjF.24.2020 ⚠
tubulin folding cofactor D, putative
— OG7
LmjF.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LmjF.20.0280 ⚠
developmentally regulated phosphoprotein-like
— OG7
LmjF.34.3900 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LmjF.23.0110 ⚠
GDP-mannose pyrophosphorylase
— OG7
LmjF.21.1770 ⚠
ATP synthase F1 subunit gamma protein, putati
— OG7
LmjF.10.1200 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.1900 ⚠
hypothetical protein, conserved
— OG7
LmjF.29.0020 ⚠
transcription factor-like protein
— OG7
Page 1 of 3
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.