LmjF.35.4810

BRCA1 C Terminus (BRCT) domain containing protein, putative
Leishmania major strain Friedlin OG6: OG6_146478 OG7: OG7_0043662 99 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 99 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.33.2740
translation initiation factor IF-2, putative
— Both
LmjF.19.1500 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.30.0730 ⚠
co-chaperone GrpE, putative
— OG7
LmjF.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmjF.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmjF.20.1090 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmjF.27.0550 ⚠
replication factor C, subunit 4, putative
— OG7
LmjF.30.2630 ⚠
replication factor C, subunit 2, putative
— OG7
LmjF.34.4030 ⚠
geranylgeranyltransferase, putative
— OG7
LmjF.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmjF.30.0735 ⚠
heat shock protein grpe
— Both
LmjF.28.1910
p21-C-terminal region-binding protein, putati
— Both
LmjF.26.2320
hypothetical protein, conserved
— Both
LmjF.08.0410
WD domain, G-beta repeat, putative
— Both
LmjF.19.1050
hypothetical protein, unknown function
— Both
LmjF.12.0510 ⚠
WW domain containing protein, putative
— Both
LmjF.11.0890
hypothetical protein, conserved
— Both
LmjF.22.0060 ⚠
transcription factor-like protein
— Both
LmjF.33.2460
Flagellum attachment zone protein 12
— Both
LmjF.33.1880
hypothetical protein, conserved
— Both
LmjF.31.0860
ras-like small GTPases, putative
— OG6
LmjF.36.4890 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.3960 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.35.2450 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.36.4370 ⚠
ubiquitin protein ligase, putative
— OG7
LmjF.06.0940 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.1955 ⚠
TLD, putative
— OG7
LmjF.15.0510 ⚠
ecotin, putative
— OG7
LmjF.15.0300 ⚠
Ecotin-like protein
— OG7
LmjF.36.3000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.29.0600 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.0730 ⚠
Outer row dynein-assembly protein 7
— OG7
LmjF.33.2260
glycosyl hydrolase-like protein
— Both
LmjF.36.6430 ⚠
protein transport protein Sec23-like protein
— OG7
LmjF.30.1205 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LmjF.01.0160 ⚠
LSM domain containing protein, putative
— OG7
LmjF.32.1070 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LmjF.35.4460 ⚠
sm-f snRNP core complex protein, putative
— OG7
LmjF.25.1705 ⚠
LSM domain containing protein, putative
— OG7
LmjF.01.0710 ⚠
ubiquitin activating enzyme, putative
— OG7
LmjF.17.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.28.2390 ⚠
WW domain containing protein, putative
— OG7
LmjF.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmjF.19.1480 ⚠
eukaryotic translation initiation factor-like
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.