LmjF.31.0860

ras-like small GTPases, putative
Leishmania major strain Friedlin OG6: OG6_478841 OG7: OG7_0000131 61 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 61 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.33.3000
hypothetical protein, unknown function
— OG6
LmjF.11.0930
hypothetical protein, conserved
— OG6
LmjF.19.1040
phenylalanyl-tRNA synthetase, putative
— OG6
LmjF.18.1220 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG6
LmjF.18.1210 ⚠
prolyl-tRNA synthetase, putative
— OG6
LmjF.07.0940
Domain of unknown function (DUF3437), putativ
— OG6
LmjF.11.0920
Short C-terminal domain/PUB domain containing
— OG6
LmjF.34.2340
asparaginyl-tRNA synthetase, putative
— OG6
LmjF.35.3200
RNA-binding protein, putative
— OG6
LmjF.33.2260
glycosyl hydrolase-like protein
— OG6
LmjF.35.4810
BRCA1 C Terminus (BRCT) domain containing pro
— OG6
LmjF.32.1090
HECT-domain (ubiquitin-transferase), putative
— OG6
LmjF.32.1040
hypothetical protein, conserved
— OG6
LmjF.33.1910
ribosome assembly protein RRB1, putative
— OG6
LmjF.35.2770
hypothetical protein, conserved
— OG6
LmjF.33.2460
Flagellum attachment zone protein 12
— OG6
LmjF.23.0543
5'-3' exoribonuclease C, putative
— OG6
LmjF.33.0410
DNA mismatch repair protein MSH2, putative
— OG6
LmjF.33.2740
translation initiation factor IF-2, putative
— OG6
LmjF.33.1880
hypothetical protein, conserved
— OG6
LmjF.35.0920
hypothetical protein, conserved
— OG6
LmjF.36.4920
hypothetical protein, conserved
— OG6
LmjF.34.2760
hypothetical protein, conserved
— OG6
LmjF.22.0060
transcription factor-like protein
— OG6
LmjF.11.0890
hypothetical protein, conserved
— OG6
LmjF.19.1050
hypothetical protein, unknown function
— OG6
LmjF.12.0510
WW domain containing protein, putative
— OG6
LmjF.08.0410
WD domain, G-beta repeat, putative
— OG6
LmjF.26.2320
hypothetical protein, conserved
— OG6
LmjF.28.1910
p21-C-terminal region-binding protein, putati
— OG6
LmjF.30.0735
heat shock protein grpe
— OG6
LmjF.16.1140
WW domain containing protein, putative
— OG6
LmjF.15.0660
hypothetical protein, conserved
— OG6
LmjF.22.0650
guide RNA associated protein, GAP2, putative
— OG6
LmjF.21.0875
hypothetical protein, conserved
— OG6
LmjF.10.0310
protein transport protein SEC23, putative
— OG6
LmjF.13.0620
hypothetical protein, conserved
— OG6
LmjF.08.0220
ubiquitin-activating enzyme-like protein
— OG6
LmjF.12.0250
cysteinyl-tRNA synthetase, putative
— OG6
LmjF.26.1470
farnesyltransferase beta subunit
— OG6
LmjF.31.0250
ATP-dependent RNA helicase, putative
— OG6
LmjF.24.2020
tubulin folding cofactor D, putative
— OG6
LmjF.15.0520
ecotin, putative
— OG6
LmjF.03.0450
TLD domain protein, conserved
— OG6
LmjF.30.0560
hypothetical protein, conserved
— OG6
LmjF.26.1220
hypothetical protein, conserved
— OG6
LmjF.18.0550
hypothetical protein, conserved
— OG6
LmjF.18.1320
hypothetical protein, conserved
— OG6
LmjF.30.0910
ubiquitin-protein ligase, putative
— OG6
LmjF.29.2360
aspartyl aminopeptidase, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.