LmjF.18.1220

bifunctional aminoacyl-tRNA synthetase, putative

Leishmania major strain Friedlin OG6: OG6_100749 OG7: OG7_0002333 190 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 190 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LmjF.18.1320 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_006238 ↔ TCSYLVIO_006246 OG6 LdBPK_181230.1 ↔ LdBPK_181300.1 OG7 LdBPK_181230.1 ↔ LdBPK_181300.1 OG7 TCSYLVIO_006238 ↔ TCSYLVIO_006246	Both
LmjF.18.0550 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_180550.1 ↔ LdBPK_181230.1 OG6 TCSYLVIO_006181 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_006181 ↔ TCSYLVIO_006246 OG7 LdBPK_180550.1 ↔ LdBPK_181230.1	Both
LmjF.33.1910 ⚠ ribosome assembly protein RRB1, putative	—	OG6 TCSYLVIO_005619 ↔ TCSYLVIO_006246 OG6 LdBPK_181230.1 ↔ LdBPK_332020.1 OG7 LdBPK_181230.1 ↔ LdBPK_332020.1 OG7 TCSYLVIO_005619 ↔ TCSYLVIO_006246	Both
LmjF.24.2020 ⚠ tubulin folding cofactor D, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_242100.1 OG6 LdBPK_181230.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_242100.1 +2 more	Both
LmjF.12.0250 ⚠ cysteinyl-tRNA synthetase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_181220.1 OG6 LdBPK_120255.1 ↔ LdBPK_181230.1 OG6 Tb927.10.12890 ↔ Tb927.6.950 OG7 Tb927.10.12890 ↔ Tb927.6.950 +2 more	Both
LmjF.34.2340 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_342110.1 OG6 LdBPK_181230.1 ↔ LdBPK_342110.1 OG7 LdBPK_181220.1 ↔ LdBPK_342110.1 OG7 LdBPK_181230.1 ↔ LdBPK_342110.1 +1 more	Both
LmjF.22.0650 ⚠ guide RNA associated protein, GAP2, putative	—	OG6 LdBPK_181230.1 ↔ LdBPK_220520.1 OG6 TCSYLVIO_001262 ↔ TCSYLVIO_006246 OG7 LdBPK_181230.1 ↔ LdBPK_220520.1 OG7 TCSYLVIO_001262 ↔ TCSYLVIO_006246	Both
LmjF.30.0460 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_342110.1 OG7 LdBPK_181230.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_006246	Both
LmjF.21.0895 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_342110.1 OG7 LdBPK_181230.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_006246	Both
LmjF.35.5390 ⚠ HECT-domain (ubiquitin-transferase), putative	—	OG7 LdBPK_181230.1 ↔ LdBPK_300970.1 OG7 LdBPK_161180.1 ↔ LdBPK_181220.1 OG7 LdBPK_161180.1 ↔ LdBPK_181230.1	OG7
LmjF.36.6710 ⚠ replication factor C subunit 3, putative	—	OG7 LdBPK_181220.1 ↔ LdBPK_241010.1 OG7 LdBPK_181230.1 ↔ LdBPK_241010.1	OG7
LmjF.32.1070 ⚠ small nuclear ribonucleoprotein, putative	—	OG7 LdBPK_181230.1 ↔ LdBPK_260010.1	OG7
LmjF.27.0550 ⚠ replication factor C, subunit 4, putative	—	OG7 LdBPK_181220.1 ↔ LdBPK_241010.1 OG7 LdBPK_181230.1 ↔ LdBPK_241010.1	OG7
LmjF.29.0600 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_181220.1 ↔ LdBPK_220007.1 OG7 LdBPK_181230.1 ↔ LdBPK_220007.1	OG7
LmjF.36.4890 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_181220.1 ↔ LdBPK_261200.1 OG7 LdBPK_181230.1 ↔ LdBPK_261200.1	OG7
LmjF.35.4460 ⚠ sm-f snRNP core complex protein, putative	—	OG7 LdBPK_181230.1 ↔ LdBPK_260010.1	OG7
LmjF.30.2630 ⚠ replication factor C, subunit 2, putative	—	OG7 LdBPK_181220.1 ↔ LdBPK_241010.1 OG7 LdBPK_181230.1 ↔ LdBPK_241010.1	OG7
LmjF.19.1500 ⚠ Eukaryotic translation initiation factor 4E-2	—	OG7 LdBPK_181220.1 ↔ LdBPK_300460.1 OG7 LdBPK_181230.1 ↔ LdBPK_300460.1	OG7
LmjF.30.0730 ⚠ co-chaperone GrpE, putative	—	OG7 LdBPK_181230.1 ↔ LdBPK_300770.1	OG7
LmjF.07.0280 ⚠ ubiquitin-protein ligase-like, putative	—	OG7 LdBPK_181230.1 ↔ LdBPK_300970.1 OG7 LdBPK_161180.1 ↔ LdBPK_181220.1 OG7 LdBPK_161180.1 ↔ LdBPK_181230.1	OG7
LmjF.25.1705 ⚠ LSM domain containing protein, putative	—	OG7 LdBPK_181230.1 ↔ LdBPK_260010.1	OG7
LmjF.33.2570 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG7 LdBPK_110640.1 ↔ LdBPK_181220.1 OG7 LdBPK_110640.1 ↔ LdBPK_181230.1	OG7
LmjF.36.0490 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	OG7
LmjF.29.0290 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	OG7
LmjF.05.0850 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	OG7
LmjF.18.0070 ⚠ zinc-finger of a C2HC-type/Double zinc ribbon	—	OG6 TCSYLVIO_006138 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	Both
LmjF.36.4230 ⚠ paraflagellar rod component, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006246	OG6
LmjF.13.0940 ⚠ N(2), N(2)-dimethylguanosine tRNA methyltrans	—	OG6 TCSYLVIO_002844 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_002844 ↔ TCSYLVIO_006246	Both
LmjF.34.2760 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_181230.1 ↔ LdBPK_342590.1 OG7 LdBPK_181230.1 ↔ LdBPK_342590.1	Both
LmjF.31.0860 ⚠ ras-like small GTPases, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_310890.1 OG6 LdBPK_181230.1 ↔ LdBPK_310890.1	OG6
LmjF.29.1700 ⚠ MORN repeat, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_291830.1 OG6 LdBPK_181230.1 ↔ LdBPK_291830.1 OG7 LdBPK_181220.1 ↔ LdBPK_291830.1 OG7 LdBPK_181230.1 ↔ LdBPK_291830.1	Both
LmjF.31.0250 ⚠ ATP-dependent RNA helicase, putative	—	OG6 LdBPK_181230.1 ↔ LdBPK_310260.1	OG6
LmjF.29.2360 ⚠ aspartyl aminopeptidase, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_292470.1 OG6 LdBPK_181230.1 ↔ LdBPK_292470.1 OG7 LdBPK_181220.1 ↔ LdBPK_292470.1 OG7 LdBPK_181230.1 ↔ LdBPK_292470.1	Both
LmjF.30.0450 ⚠ Eukaryotic translation initiation factor 4E-4	—	OG6 LdBPK_181220.1 ↔ LdBPK_300460.1 OG6 LdBPK_181230.1 ↔ LdBPK_300460.1 OG7 LdBPK_181220.1 ↔ LdBPK_300460.1 OG7 LdBPK_181230.1 ↔ LdBPK_300460.1	Both
LmjF.36.1380 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_181220.1 ↔ LdBPK_361430.1 OG6 LdBPK_181230.1 ↔ LdBPK_361430.1 OG7 LdBPK_181220.1 ↔ LdBPK_361430.1 OG7 LdBPK_181230.1 ↔ LdBPK_361430.1	Both
LmjF.33.1880 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_181220.1 ↔ LdBPK_331980.1 OG6 LdBPK_181230.1 ↔ LdBPK_331980.1 OG7 LdBPK_181220.1 ↔ LdBPK_331980.1 OG7 LdBPK_181230.1 ↔ LdBPK_331980.1	Both
LmjF.35.0920 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_181230.1 ↔ LdBPK_350940.1 OG7 LdBPK_181230.1 ↔ LdBPK_350940.1	Both
LmjF.30.0560 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_181220.1 ↔ LdBPK_300580.1 OG6 LdBPK_181230.1 ↔ LdBPK_300580.1 OG7 LdBPK_181220.1 ↔ LdBPK_300580.1 OG7 LdBPK_181230.1 ↔ LdBPK_300580.1	Both
LmjF.36.4920 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_181230.1 ↔ LdBPK_365150.1 OG7 LdBPK_181230.1 ↔ LdBPK_365150.1	Both
LmjF.01.0610 ⚠ DNA-damage inducible protein DDI1-like protei	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_006246	Both
LmjF.30.1230 ⚠ Zinc finger, C3HC4 type (RING finger), putati	—	OG6 TCSYLVIO_003179 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_003179 ↔ TCSYLVIO_006246	Both
LmjF.02.0310 ⚠ Soluble NSF attachment protein, SNAP, putativ	—	OG6 LdBPK_020280.1 ↔ LdBPK_181220.1 OG6 LdBPK_020280.1 ↔ LdBPK_181230.1 OG7 LdBPK_020280.1 ↔ LdBPK_181220.1 OG7 LdBPK_020280.1 ↔ LdBPK_181230.1	Both
LmjF.08.0410 ⚠ WD domain, G-beta repeat, putative	—	OG6 LdBPK_080420.1 ↔ LdBPK_181220.1 OG6 LdBPK_080420.1 ↔ LdBPK_181230.1 OG7 LdBPK_080420.1 ↔ LdBPK_181220.1 OG7 LdBPK_080420.1 ↔ LdBPK_181230.1	Both
LmjF.12.0510 ⚠ WW domain containing protein, putative	—	OG6 LdBPK_120470.1 ↔ LdBPK_181220.1 OG6 LdBPK_120470.1 ↔ LdBPK_181230.1 OG7 LdBPK_120470.1 ↔ LdBPK_181220.1 OG7 LdBPK_120470.1 ↔ LdBPK_181230.1	Both
LmjF.11.0890 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_110890.1 ↔ LdBPK_181220.1 OG6 LdBPK_110890.1 ↔ LdBPK_181230.1 OG7 LdBPK_110890.1 ↔ LdBPK_181220.1 OG7 LdBPK_110890.1 ↔ LdBPK_181230.1	Both
LmjF.07.0940 ⚠ Domain of unknown function (DUF3437), putativ	—	OG6 LdBPK_071090.1 ↔ LdBPK_181220.1 OG6 LdBPK_071090.1 ↔ LdBPK_181230.1 OG7 LdBPK_071090.1 ↔ LdBPK_181220.1 OG7 LdBPK_071090.1 ↔ LdBPK_181230.1	Both
LmjF.23.0490 ⚠ 5'-AMP-activated protein kinase subunit beta,	—	OG6 LdBPK_181220.1 ↔ LdBPK_230530.1 OG6 LdBPK_181230.1 ↔ LdBPK_230530.1 OG7 LdBPK_181220.1 ↔ LdBPK_230530.1 OG7 LdBPK_181230.1 ↔ LdBPK_230530.1	Both
LmjF.22.0590 ⚠ Uncharacterised protein family UPF0066, putat	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_006246	Both
LmjF.18.1040 ⚠ 5-oxoprolinase, putative	—	OG6 LdBPK_181050.1 ↔ LdBPK_181220.1 OG6 LdBPK_181050.1 ↔ LdBPK_181230.1 OG7 LdBPK_181050.1 ↔ LdBPK_181220.1 OG7 LdBPK_181050.1 ↔ LdBPK_181230.1	Both
LmjF.11.0920 ⚠ Short C-terminal domain/PUB domain containing	—	OG6 LdBPK_110920.1 ↔ LdBPK_181220.1 OG6 LdBPK_110920.1 ↔ LdBPK_181230.1 OG7 LdBPK_110920.1 ↔ LdBPK_181220.1 OG7 LdBPK_110920.1 ↔ LdBPK_181230.1	Both

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