LmjF.18.1040

5-oxoprolinase, putative
Leishmania major strain Friedlin OG6: OG6_100892 OG7: OG7_0005437 122 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 122 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.23.1630 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.35.2340 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.24.0650 ⚠
PPPDE putative peptidase domain containing pr
— Both
LmjF.31.2170
ARM-like helical domain-containing protein
— Both
LmjF.17.0725 ⚠
GMP reductase
— OG6
LmjF.21.0470
vacuolar sorting-associated-like protein
— Both
LmjF.35.2770
hypothetical protein, conserved
— Both
LmjF.36.2850
hypothetical protein, conserved
— Both
LmjF.22.0060 ⚠
transcription factor-like protein
— Both
LmjF.33.2740
translation initiation factor IF-2, putative
— Both
LmjF.19.1040
phenylalanyl-tRNA synthetase, putative
— Both
LmjF.36.2480
hypothetical protein, conserved
— Both
LmjF.29.1700 ⚠
MORN repeat, putative
— Both
LmjF.29.2360
aspartyl aminopeptidase, putative
— Both
LmjF.27.1350
hypothetical protein, unknown function
— Both
LmjF.36.1380
hypothetical protein, conserved
— Both
LmjF.33.1880
hypothetical protein, conserved
— Both
LmjF.24.2020
tubulin folding cofactor D, putative
— Both
LmjF.30.0560
hypothetical protein, conserved
— Both
LmjF.23.0490
5'-AMP-activated protein kinase subunit beta,
— Both
LmjF.09.1300 ⚠
PPPDE putative peptidase domain containing pr
— Both
LmjF.24.0490
Leucine Rich repeats (2 copies)/Leucine rich
— Both
LmjF.29.1100 ⚠
Ankyrin repeats (3 copies), putative
— Both
LmjF.35.3070
hypothetical protein, conserved
— Both
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.18.1330 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LmjF.33.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.35.4260 ⚠
predicted zinc finger protein
— OG7
LmjF.34.3550 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmjF.33.0140 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.18.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.04.0520 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LmjF.34.4280 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.03.0480 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LmjF.35.2670 ⚠
ankyrin repeat protein, putative
— OG7
LmjF.30.3260 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.36.3000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmjF.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmjF.31.0360 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LmjF.10.0195 ⚠
hypothetical protein, conserved
— OG7
LmjF.14.1170 ⚠
ras-like small GTPases, putative
— OG7
LmjF.34.3900 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.13.0870 ⚠
mitochondrial processing peptidase alpha subu
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.