LmjF.15.0660

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_199742 OG7: OG7_0083851 140 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 140 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— OG7
LmjF.31.3180 ⚠
histone H4
— Both
LmjF.02.0020 ⚠
histone H4
— Both
LmjF.36.0020 ⚠
histone H4
— Both
LmjF.15.0010 ⚠
histone H4
— Both
LmjF.06.0010 ⚠
histone H4
— Both
LmjF.01.0610
DNA-damage inducible protein DDI1-like protei
— Both
LmjF.11.0930
hypothetical protein, conserved
— Both
LmjF.13.0640 ⚠
hypothetical protein, conserved
— Both
LmjF.14.1360
inositol-3-phosphate synthase
— Both
LmjF.07.0940
Domain of unknown function (DUF3437), putativ
— Both
LmjF.11.0920
Short C-terminal domain/PUB domain containing
— Both
LmjF.12.0510 ⚠
WW domain containing protein, putative
— Both
LmjF.08.0410
WD domain, G-beta repeat, putative
— Both
LmjF.12.0280
ornithine decarboxylase, putative
— Both
LmjF.29.2060 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.2600 ⚠
acyl-CoA binding protein, putative
— OG7
LmjF.17.0780 ⚠
Acyl CoA binding protein, putative
— OG7
LmjF.17.0620 ⚠
Acyl CoA binding protein, putative
— OG7
LmjF.28.2390 ⚠
WW domain containing protein, putative
— OG7
LmjF.17.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.35.5210 ⚠
GTP-binding protein, putative
— OG7
LmjF.05.0460 ⚠
GTPase, putative
— OG7
LmjF.33.2400 ⚠
ras-like small GTPases, putative
— OG7
LmjF.26.1370 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LmjF.21.0015 ⚠
histone H4
— OG7
LmjF.36.6430 ⚠
protein transport protein Sec23-like protein
— OG7
LmjF.36.3000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.15.0300 ⚠
Ecotin-like protein
— OG7
LmjF.15.0510 ⚠
ecotin, putative
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.15.0360 ⚠
RNA pseudouridylate synthase, putative
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.10.0890 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LmjF.04.0250 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LmjF.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmjF.22.1430 ⚠
fk506-binding protein 1-like protein
— OG7
LmjF.19.0970 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LmjF.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmjF.19.1530 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LmjF.03.0060 ⚠
Met-10+ like-protein, putative
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.27.1690 ⚠
mRNA export factor MEX67
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.05.0710 ⚠
CYC2-like cyclin, putative
— OG7
LmjF.22.0450 ⚠
Acetyltransferase (GNAT) family, putative
— OG7
LmjF.06.0940 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.1955 ⚠
TLD, putative
— OG7
LmjF.32.0730 ⚠
Outer row dynein-assembly protein 7
— OG7
LmjF.20.1090 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.