LmjF.31.3180

histone H4
Leishmania major strain Friedlin OG6: OG6_100120 OG7: OG7_0002354 87 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 87 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.29.1720 ⚠
histone H2A, putative
— Both
LmjF.15.0360 ⚠
RNA pseudouridylate synthase, putative
— OG7
LmjF.26.1370 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LmjF.33.2400 ⚠
ras-like small GTPases, putative
— OG7
LmjF.05.0460 ⚠
GTPase, putative
— OG7
LmjF.35.5210 ⚠
GTP-binding protein, putative
— OG7
LmjF.17.0280 ⚠
histone H2A variant Z
— OG7
LmjF.21.0915 ⚠
histone H2A
— Both
LmjF.29.1740 ⚠
histone H2A, putative
— Both
LmjF.21.0930 ⚠
histone H2A, putative
— Both
LmjF.21.0920 ⚠
histone H2A, putative
— Both
LmjF.10.0890 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LmjF.29.1730 ⚠
histone H2A, putative
— Both
LmjF.01.0610 ⚠
DNA-damage inducible protein DDI1-like protei
— Both
LmjF.24.0330 ⚠
Mitochondrial small ribosomal subunit Rsm22,
— Both
LmjF.16.0310 ⚠
Met-10+ like-protein, putative
— Both
LmjF.24.1100 ⚠
pre-mRNA-splicing factor ATP-dependent RNA he
— OG6
LmjF.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— +1 more Both
LmjF.13.0640 ⚠
hypothetical protein, conserved
— Both
LmjF.15.0690 ⚠
hypothetical protein, conserved
— Both
LmjF.29.2150 ⚠
cdc2-related kinase 10, putative
— Both
LmjF.30.2040 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmjF.19.0970 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LmjF.05.0710 ⚠
CYC2-like cyclin, putative
— OG7
LmjF.17.0620 ⚠
Acyl CoA binding protein, putative
— OG7
LmjF.17.0780 ⚠
Acyl CoA binding protein, putative
— OG7
LmjF.34.2600 ⚠
acyl-CoA binding protein, putative
— OG7
LmjF.29.2060 ⚠
hypothetical protein, conserved
— OG7
LmjF.27.1690 ⚠
mRNA export factor MEX67
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.22.0450 ⚠
Acetyltransferase (GNAT) family, putative
— OG7
LmjF.03.0060 ⚠
Met-10+ like-protein, putative
— OG7
LmjF.19.1530 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LmjF.31.1410 ⚠
hypothetical protein, conserved
— Both
LmjF.22.1430 ⚠
fk506-binding protein 1-like protein
— OG7
LmjF.31.1130 ⚠
amidohydrolase, putative
— OG7
LmjF.24.1880 ⚠
cyclin 11, putative
— OG7
LmjF.25.0870 ⚠
Atypical serine/threonine protein kinase BUD3
— OG7
LmjF.33.0770 ⚠
G1 cyclin CycE4, putative
— OG7
LmjF.32.0820 ⚠
CYC2-like cyclin, putative
— OG7
LmjF.36.0230 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LmjF.30.3630 ⚠
CYC2-like protein, putative
— OG7
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— OG7
LmjF.04.0250 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LmjF.36.6220 ⚠
flagellum transition zone component, putative
— Both
LmjF.17.0940 ⚠
Phosphorylated CTD interacting factor 1 WW do
— Both
LmjF.36.2830 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
LmjF.33.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LmjF.25.0800 ⚠
DNL zinc finger, putative
— Both
LmjF.29.1240 ⚠
Hsp70 protein/TPR repeat, putative
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.