LmjF.31.1130

amidohydrolase, putative
Leishmania major strain Friedlin OG6: OG6_103201 OG7: OG7_0005942 180 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 180 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.11.0630 ⚠
metallo-peptidase, Clan MF, Family M17
— +4 more OG7
LmjF.33.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— +4 more OG7
LmjF.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— +4 more OG7
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— OG7
LmjF.28.0330 ⚠
rrp44p homologue, putative
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.36.5620 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
LmjF.36.6430 ⚠
protein transport protein Sec23-like protein
— OG7
LmjF.35.4150 ⚠
elongation factor 1-alpha, putative
— OG7
LmjF.17.1310 ⚠
methyltransferase domain containing protein,
— OG7
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.14.1360 ⚠
inositol-3-phosphate synthase
— OG7
LmjF.20.0705 ⚠
conserved protein, unknown function
— OG7
LmjF.36.5140 ⚠
VHS domain containing protein, putative
— OG7
LmjF.06.0010 ⚠
histone H4
— OG7
LmjF.21.0015 ⚠
histone H4
— OG7
LmjF.15.0010 ⚠
histone H4
— OG7
LmjF.36.0020 ⚠
histone H4
— OG7
LmjF.02.0020 ⚠
histone H4
— OG7
LmjF.31.3180 ⚠
histone H4
— OG7
LmjF.25.2450 ⚠
histone H4
— OG7
LmjF.35.1310 ⚠
histone H4
— OG7
LmjF.20.0620 ⚠
Quinonprotein alcohol dehydrogenase-like prot
— OG7
LmjF.12.0280 ⚠
ornithine decarboxylase, putative
— OG7
LmjF.34.0150 ⚠
malate dehydrogenase, putative
— OG7
LmjF.34.0160 ⚠
mitochondrial malate dehydrogenase
— OG7
LmjF.34.0130 ⚠
malate dehydrogenase, putative
— OG7
LmjF.19.0710 ⚠
glycosomal malate dehydrogenase
— OG7
LmjF.29.1240 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LmjF.15.0040 ⚠
Possible lysine decarboxylase, putative
— OG7
LmjF.26.1220 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.3070 ⚠
tRNA (Guanine-1)-methyltransferase, putative
— OG7
LmjF.17.0083 ⚠
elongation factor 1-alpha
— OG7
LmjF.33.1400 ⚠
STE/STE11 serine/threonine-protein kinase, pu
— OG7
LmjF.36.6220 ⚠
flagellum transition zone component, putative
— OG7
LmjF.30.0470 ⚠
hypothetical protein, conserved
— OG7
LmjF.17.0081 ⚠
elongation factor 1-alpha
— OG7
LmjF.26.0470 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.2260 ⚠
glycosyl hydrolase-like protein
— OG7
LmjF.05.0710 ⚠
CYC2-like cyclin, putative
— OG7
LmjF.35.1990 ⚠
U3 small nucleolar RNA-associated protein 6,
— OG7
LmjF.27.1680 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.0730 ⚠
Outer row dynein-assembly protein 7
— OG7
LmjF.26.1290 ⚠
Cupin-like domain containing protein, putativ
— OG7
LmjF.22.1290 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
LmjF.36.2130 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LmjF.11.1170 ⚠
eukaryotic release factor 3, putative
— OG7
LmjF.25.0800 ⚠
DNL zinc finger, putative
— OG7
LmjF.34.0140 ⚠
malate dehydrogenase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.