LmjF.20.0705

conserved protein, unknown function
Leishmania major strain Friedlin OG6: OG6_173713 OG7: OG7_0063852 99 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 99 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.26.1290
Cupin-like domain containing protein, putativ
— Both
LmjF.35.3500 ⚠
zinc finger protein, putative
— OG7
LmjF.08.0080 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LmjF.17.0082 ⚠
elongation factor 1-alpha
— OG7
LmjF.35.3100 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.07.0340 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmjF.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmjF.14.1170 ⚠
ras-like small GTPases, putative
— OG7
LmjF.35.4260 ⚠
predicted zinc finger protein
— OG7
LmjF.32.0400 ⚠
ATP-dependent RNA helicase HEL67
— OG7
LmjF.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.28.0330 ⚠
rrp44p homologue, putative
— OG7
LmjF.33.1710 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
LmjF.22.0810 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
LmjF.28.2000 ⚠
protein lipid droplet kinase (LDK)
— OG7
LmjF.07.0900 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
LmjF.36.0900 ⚠
SNF1-related protein kinases, putative
— OG7
LmjF.21.0150 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
LmjF.18.0640 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
LmjF.17.1450 ⚠
Rab-GTPase-TBC domain containing protein, put
— Both
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— Both
LmjF.11.1170 ⚠
eukaryotic release factor 3, putative
— OG7
LmjF.15.0980
DNA repair protein Rad9, putative
— OG7
LmjF.26.1160 ⚠
RNA pseudouridylate synthase, putative
— OG7
LmjF.04.0250 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LmjF.36.0470 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LmjF.34.1140 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.30.2840 ⚠
GTPase activator-like protein
— OG7
LmjF.31.1930 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.36.6430 ⚠
protein transport protein Sec23-like protein
— OG7
LmjF.32.0730 ⚠
Outer row dynein-assembly protein 7
— OG7
LmjF.17.0080 ⚠
elongation factor 1-alpha
— OG7
LmjF.34.0310 ⚠
tRNA pseudouridine synthase, putative
— OG7
LmjF.35.4550
hypothetical protein, conserved
— Both
LmjF.36.2130 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LmjF.17.0081 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0083 ⚠
elongation factor 1-alpha
— OG7
LmjF.19.1020 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LmjF.10.0140 ⚠
DEAD/DEAH box helicase, putative
— OG7
LmjF.26.0420 ⚠
pseudouridylate synthase-like protein
— OG7
LmjF.31.1130 ⚠
amidohydrolase, putative
— OG7
LmjF.17.0084 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0086 ⚠
elongation factor 1-alpha
— OG7
LmjF.36.4890 ⚠
hypothetical protein, conserved
— OG7
LmjF.17.0085 ⚠
elongation factor 1-alpha
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.