LmjF.26.0420

pseudouridylate synthase-like protein
Leishmania major strain Friedlin OG6: OG6_133986 OG7: OG7_0002342 137 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 137 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.33.1910 ⚠
ribosome assembly protein RRB1, putative
— OG7
LmjF.31.1130 ⚠
amidohydrolase, putative
— OG7
LmjF.35.1190 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LmjF.18.1210 ⚠
prolyl-tRNA synthetase, putative
— OG7
LmjF.30.2320 ⚠
SET domain containing protein, putative
— OG7
LmjF.36.3420 ⚠
vacuolar protein sorting-associated protein-l
— OG7
LmjF.32.2730 ⚠
hypothetical protein, conserved
— OG7
LmjF.13.0940 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— OG7
LmjF.26.2320 ⚠
hypothetical protein, conserved
— OG7
LmjF.05.0610 ⚠
Surp module, putative
— OG7
LmjF.07.0830 ⚠
hypothetical protein, conserved
— OG7
LmjF.07.0840 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.0460 ⚠
hypothetical protein, unknown function
— OG7
LmjF.07.0820 ⚠
hypothetical protein, unknown function
— OG7
LmjF.20.0705 ⚠
conserved protein, unknown function
— OG7
LmjF.28.1100 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmjF.36.6430 ⚠
protein transport protein Sec23-like protein
— OG7
LmjF.10.0310 ⚠
protein transport protein SEC23, putative
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.11.1120 ⚠
hypothetical protein, conserved
— OG7
LmjF.11.0630 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.33.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.22.0650 ⚠
guide RNA associated protein, GAP2, putative
— OG7
LmjF.18.0650 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
LmjF.24.1170 ⚠
hypothetical protein, conserved
— OG7
LmjF.01.0610 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
LmjF.15.0360 ⚠
RNA pseudouridylate synthase, putative
— OG7
LmjF.04.0250 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LmjF.26.1160 ⚠
RNA pseudouridylate synthase, putative
— OG7
LmjF.30.1380 ⚠
amidohydrolase, putative
— OG7
LmjF.20.1550 ⚠
amidohydrolase, putative
— OG7
LmjF.20.1560 ⚠
amidohydrolase, putative
— OG7
LmjF.34.3960 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.25.1020 ⚠
dehydrogenase-like protein
— OG7
LmjF.05.0860 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.3380 ⚠
tRNA pseudouridine synthase D (TruD), putativ
— OG7
LmjF.36.2170 ⚠
NOL1/NOP2/sun family, putative
— OG7
LmjF.30.3360 ⚠
calmodulin-related protein, putative
— OG7
LmjF.35.2450 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.32.2390 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.2980 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.1090 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.26.1280 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.3220 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.3670 ⚠
vacuolar ATP synthase catalytic subunit A, pu
— OG7
LmjF.30.1850 ⚠
phosphatidylinositol kinase, putative
— OG7
LmjF.36.4370 ⚠
ubiquitin protein ligase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.