LmjF.35.5210

GTP-binding protein, putative
Leishmania major strain Friedlin OG6: OG6_101533 OG7: OG7_0001608 236 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 236 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.33.1400 ⚠
STE/STE11 serine/threonine-protein kinase, pu
— OG7
LmjF.07.0100 ⚠
metallo-peptidase, Clan ME, Family M16C
— OG7
LmjF.12.0060 ⚠
ribonuclease mar1
— OG7
LmjF.17.0940 ⚠
Phosphorylated CTD interacting factor 1 WW do
— OG7
LmjF.27.0940 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LmjF.05.0710 ⚠
CYC2-like cyclin, putative
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmjF.36.0180 ⚠
elongation factor 2
— OG7
LmjF.34.4540 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
LmjF.33.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.17.0620 ⚠
Acyl CoA binding protein, putative
— OG7
LmjF.17.0780 ⚠
Acyl CoA binding protein, putative
— OG7
LmjF.10.1140 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmjF.25.0800 ⚠
DNL zinc finger, putative
— OG7
LmjF.30.2270 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.29.1240 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LmjF.20.1550 ⚠
amidohydrolase, putative
— OG7
LmjF.15.0010 ⚠
histone H4
— OG7
LmjF.36.0020 ⚠
histone H4
— OG7
LmjF.11.0150 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.2600 ⚠
acyl-CoA binding protein, putative
— OG7
LmjF.12.0280 ⚠
ornithine decarboxylase, putative
— OG7
LmjF.28.1220 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.1480 ⚠
Mitochondrial glycoprotein, putative
— OG7
LmjF.26.0470 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.0190 ⚠
elongation factor 2
— OG7
LmjF.30.0470 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.4370 ⚠
ubiquitin protein ligase, putative
— OG7
LmjF.36.6220 ⚠
flagellum transition zone component, putative
— OG7
LmjF.08.0310 ⚠
Isochorismatase family, putative
— OG7
LmjF.15.0690 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0060 ⚠
Met-10+ like-protein, putative
— OG7
LmjF.26.0630 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.0450 ⚠
Acetyltransferase (GNAT) family, putative
— OG7
LmjF.13.0640 ⚠
hypothetical protein, conserved
— OG7
LmjF.18.1150 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmjF.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.34.3960 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.27.1690 ⚠
mRNA export factor MEX67
— OG7
LmjF.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.22.1130 ⚠
Beta-lactamase superfamily domain containing
— OG7
LmjF.16.0310 ⚠
Met-10+ like-protein, putative
— OG7
LmjF.18.1570 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmjF.27.2630 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG7
LmjF.19.0220 ⚠
polyprenyl synthase, putative
— OG7
LmjF.29.2060 ⚠
hypothetical protein, conserved
— OG7
LmjF.29.1270 ⚠
Heat shock protein 100 kDa
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.