LmjF.27.1340

hypothetical protein, unknown function
Leishmania major strain Friedlin OG6: OG6_200140 OG7: OG7_0052146 70 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 70 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.12.0250
cysteinyl-tRNA synthetase, putative
— OG7
LmjF.18.0350
ATP12 chaperone protein, putative
— OG7
LmjF.36.2420
serine peptidase, Clan SC, Family S9B
— OG7
LmjF.08.0220 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LmjF.15.1210 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LmjF.35.4230 ⚠
synaptojanin (N-terminal domain), putative
— OG7
LmjF.10.0160
hypothetical protein, conserved
— OG7
LmjF.35.0830 ⚠
NADH-dependent fumarate reductase-like protei
— OG7
LmjF.36.1150 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LmjF.07.0800 ⚠
flavoprotein subunit-like protein
— OG7
LmjF.08.0410
WD domain, G-beta repeat, putative
— OG7
LmjF.09.0740
ubiquitin ligase, putative
— OG7
LmjF.35.3370
hypothetical protein, conserved
— OG7
LmjF.23.0110
GDP-mannose pyrophosphorylase
— OG7
LmjF.34.1990
Zeta toxin, putative
— OG7
LmjF.19.1040
phenylalanyl-tRNA synthetase, putative
— OG7
LmjF.34.1220 ⚠
inositol 5-phosphatase-like protein
— OG7
LmjF.35.1180 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LmjF.01.0610
DNA-damage inducible protein DDI1-like protei
— OG7
LmjF.15.0280
ribonucleoprotein p18, mitochondrial precurso
— OG7
LmjF.34.4090
GRIP domain containing protein, putative
— OG7
LmjF.11.0990 ⚠
adaptin-related protein-like protein
— OG7
LmjF.36.5260 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
LmjF.36.6770 ⚠
beta adaptin, putative
— OG7
LmjF.24.2020
tubulin folding cofactor D, putative
— OG7
LmjF.10.1200 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.1900 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.1910
ribosome assembly protein RRB1, putative
— OG7
LmjF.36.3090
hypothetical protein, conserved
— OG7
LmjF.35.1190 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LmjF.05.0180
dihydrolipoamide branched chain transacylase,
— OG7
LmjF.24.0820 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LmjF.32.0210
Histone chaperone Rttp106-like, putative
— OG7
LmjF.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LmjF.29.0020
transcription factor-like protein
— OG7
LmjF.07.0760 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LmjF.23.1165
coronin, putative
— OG7
LmjF.32.0870
phenylalanyl-tRNA synthetase alpha chain, put
— OG7
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG7
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG7
LmjF.35.0700
vacuolar ATP synthase subunit d, putative
— OG7
LmjF.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.35.2340 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.23.1630 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.34.4290
nucleolar protein family a, putative
— OG7
LmjF.26.0310 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LmjF.36.0150 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LmjF.03.0800 ⚠
6-phosphofructo-2-kinase 1
— OG7
LmjF.30.0560
hypothetical protein, conserved
— OG7
LmjF.34.2360
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.