LmjF.30.1550

pseudouridine synthase A-like protein, putative
Leishmania major strain Friedlin OG6: OG6_100424 OG7: OG7_0002342 141 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 141 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.33.1910 ⚠
ribosome assembly protein RRB1, putative
— Both
LmjF.13.0940 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— OG7
LmjF.18.1220 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LmjF.35.1860 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.21.1650 ⚠
protein kinase PK4, putative
— OG7
LmjF.33.1830 ⚠
dual specificity tyrosine-phosphorylation-reg
— OG7
LmjF.15.0180 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.21.1430 ⚠
2-oxoisovalerate dehydrogenase alpha subunit,
— OG7
LmjF.35.1180 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LmjF.36.0150 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LmjF.36.3100 ⚠
ATP synthase, putative
— OG7
LmjF.36.0080 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LmjF.21.1340 ⚠
ATP synthase, putative
— OG7
LmjF.18.0550 ⚠
hypothetical protein, conserved
— OG7
LmjF.29.0290 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmjF.36.0490 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmjF.36.5420 ⚠
branch point binding protein, putative
— OG7
LmjF.35.0830 ⚠
NADH-dependent fumarate reductase-like protei
— OG7
LmjF.10.0160 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.4250 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.25.0010 ⚠
beta galactofuranosyl transferase
— OG7
LmjF.35.0900 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.0550 ⚠
galactofuranosyltransferase lpg1-like protein
— OG7
LmjF.35.2940 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG7
LmjF.26.0310 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LmjF.14.1070 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.18.0070 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— OG7
LmjF.07.0800 ⚠
flavoprotein subunit-like protein
— OG7
LmjF.29.0020 ⚠
transcription factor-like protein
— OG7
LmjF.18.1320 ⚠
hypothetical protein, conserved
— OG7
LmjF.29.0320 ⚠
TPR repeat, putative
— OG7
LmjF.05.0850 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmjF.14.0830 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.25.2210 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.1190 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LmjF.18.1210 ⚠
prolyl-tRNA synthetase, putative
— OG7
LmjF.25.1020 ⚠
dehydrogenase-like protein
— OG7
LmjF.28.1620 ⚠
tRNA pseudouridine synthase D (TruD), putativ
— OG7
LmjF.30.0180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
LmjF.29.2540 ⚠
NOL1/NOP2/sun family, putative
— OG7
LmjF.17.1130 ⚠
NOL1/NOP2/sun family, putative
— OG7
LmjF.33.0080 ⚠
hypothetical protein, conserved
— OG7
LmjF.18.1110 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LmjF.36.3260 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.0330 ⚠
Mitochondrial small ribosomal subunit Rsm22,
— OG7
LmjF.30.3220 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.3960 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.36.4370 ⚠
ubiquitin protein ligase, putative
— OG7
LmjF.35.2450 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.34.3670 ⚠
vacuolar ATP synthase catalytic subunit A, pu
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.