LmjF.35.2940

Leucine carboxyl methyltransferase/Cupin-like domain containing protein, putative
Leishmania major strain Friedlin OG6: OG6_106314 OG7: OG7_0005126 100 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 100 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.36.4230 ⚠
paraflagellar rod component, putative
— Both
LmjF.04.0450 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LmjF.20.1180 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmjF.36.0150 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LmjF.26.0310 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LmjF.03.0800 ⚠
6-phosphofructo-2-kinase 1
— Both
LmjF.07.0760 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
LmjF.33.0550 ⚠
hypothetical protein, conserved
— Both
LmjF.28.0940 ⚠
oxidoreductase-like protein
— Both
LmjF.20.1185 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmjF.24.2020 ⚠
tubulin folding cofactor D, putative
— Both
LmjF.04.0350 ⚠
hypothetical protein, conserved
— Both
LmjF.16.0730 ⚠
ubiquitin hydrolase, putative
— Both
LmjF.22.0650 ⚠
guide RNA associated protein, GAP2, putative
— Both
LmjF.06.0810 ⚠
hypothetical protein, unknown function
— Both
LmjF.13.0940 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
LmjF.22.0590 ⚠
Uncharacterised protein family UPF0066, putat
— Both
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmjF.30.1230 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— Both
LmjF.23.1680 ⚠
Inositol hexakisphosphate, putative
— Both
LmjF.27.1940
cdc2-related kinase 9
— OG6
LmjF.01.0610 ⚠
DNA-damage inducible protein DDI1-like protei
— Both
LmjF.28.2730 ⚠
hypothetical protein, conserved
— Both
LmjF.36.5640 ⚠
Cyclin 12, L-type
— Both
LmjF.36.5760 ⚠
Rab3 GTPase-activating protein regulatory sub
— Both
LmjF.36.0130 ⚠
PUB domain containing protein, putative
— Both
LmjF.36.4670 ⚠
hypothetical protein, conserved
— Both
LmjF.35.3360 ⚠
Putative death-receptor fusion protein (DUF24
— Both
LmjF.28.2820 ⚠
heat shock protein 70, putative
— Both
LmjF.10.0160 ⚠
hypothetical protein, conserved
— OG7
LmjF.31.1340 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
LmjF.31.1370 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.0500 ⚠
hypothetical protein, conserved
— OG7
LmjF.05.0150 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.0760 ⚠
cyclin 9, putative
— OG7
LmjF.30.0150 ⚠
Leucine-rich repeat, ribonuclease inhibitor s
— OG7
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmjF.14.0830 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.05.0850 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmjF.14.1070 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.36.4250 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.06.0190 ⚠
hypothetical protein, conserved
— Both
LmjF.36.0490 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmjF.29.0290 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmjF.15.0180 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.33.1830 ⚠
dual specificity tyrosine-phosphorylation-reg
— OG7
LmjF.35.1860 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.26.0420 ⚠
pseudouridylate synthase-like protein
— OG7
LmjF.19.1020 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.