LmjF.36.5640

Cyclin 12, L-type
Leishmania major strain Friedlin OG6: OG6_144751 OG7: OG7_0001363 94 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 94 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.01.0430 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LmjF.24.0620 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.21.0400 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LmjF.30.1200 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.25.1315 ⚠
DNA-directed RNA polymerase I subunit RPB10,
— Both
LmjF.13.1120 ⚠
DNA-directed RNA polymerase I subunit, putati
— Both
LmjF.30.3430 ⚠
protein mkt1, putative
— Both
LmjF.06.0190 ⚠
hypothetical protein, conserved
— Both
LmjF.29.2670
Serine/threonine-protein kinase NEK6, putativ
— OG6
LmjF.35.3360 ⚠
Putative death-receptor fusion protein (DUF24
— Both
LmjF.06.0810 ⚠
hypothetical protein, unknown function
— Both
LmjF.18.1450 ⚠
Protein of unknown function (DUF3648), putati
— Both
LmjF.17.0170 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.15.0920 ⚠
protein phosphatase 2A regulatory subunit, pu
— Both
LmjF.16.0730 ⚠
ubiquitin hydrolase, putative
— Both
LmjF.04.0350 ⚠
hypothetical protein, conserved
— Both
LmjF.22.1500
ATP-dependent DEAD/H RNA helicase, putative
— OG6
LmjF.23.1680 ⚠
Inositol hexakisphosphate, putative
— Both
LmjF.35.2180 ⚠
hypothetical protein, conserved
— Both
LmjF.27.1940
cdc2-related kinase 9
— OG6
LmjF.28.2730 ⚠
hypothetical protein, conserved
— Both
LmjF.34.1540
kinesin, putative
— OG6
LmjF.08.0910 ⚠
Beta-lactamase superfamily domain containing
— Both
LmjF.09.0980 ⚠
hypothetical protein, conserved
— Both
LmjF.35.0950 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LmjF.21.0820 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LmjF.31.1340 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
LmjF.36.0080 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LmjF.34.3280 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LmjF.09.1170 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.34.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.34.2150 ⚠
eukaryotic translation initiation factor 2-al
— OG7
LmjF.36.4560 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.35.5000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.11.0140 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LmjF.01.0350 ⚠
hypothetical protein, conserved
— Both
LmjF.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.32.1550 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.36.7000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.29.1120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmjF.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmjF.35.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmjF.27.0550 ⚠
replication factor C, subunit 4, putative
— OG7
LmjF.24.0990 ⚠
replication factor C, subunit 1, putative
— OG7
LmjF.30.2630 ⚠
replication factor C, subunit 2, putative
— OG7
LmjF.24.0300 ⚠
hypothetical protein, conserved
— Both
LmjF.33.2910 ⚠
hypothetical protein, conserved
— Both
LmjF.35.1620 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.