LmjF.29.2670

Serine/threonine-protein kinase NEK6, putative
Leishmania major strain Friedlin OG6: OG6_147247 OG7: OG7_0001157 39 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 39 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.30.3430
protein mkt1, putative
— OG6
LmjF.04.0350
hypothetical protein, conserved
— OG6
LmjF.16.0730
ubiquitin hydrolase, putative
— OG6
LmjF.15.0920
protein phosphatase 2A regulatory subunit, pu
— OG6
LmjF.01.0430
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG6
LmjF.18.1450
Protein of unknown function (DUF3648), putati
— OG6
LmjF.35.3360
Putative death-receptor fusion protein (DUF24
— OG6
LmjF.35.1730
casein kinase II, putative
— OG6
LmjF.36.0970
hypothetical protein, conserved
— OG6
LmjF.36.5760
Rab3 GTPase-activating protein regulatory sub
— OG6
LmjF.25.1970
kinesin, putative
— OG6
LmjF.36.5640
Cyclin 12, L-type
— OG6
LmjF.30.2440
hypothetical protein, conserved
— OG6
LmjF.36.2480
hypothetical protein, conserved
— OG6
LmjF.33.2910
hypothetical protein, conserved
— OG6
LmjF.36.6140
hypothetical protein, conserved
— OG6
LmjF.30.2730
Stabilization of polarity axis, putative
— OG6
LmjF.33.2560
Unc104-like kinesin, putative
— OG6
LmjF.34.0300
hypothetical protein, conserved
— OG6
LmjF.06.0190
hypothetical protein, conserved
— OG6
LmjF.08.0110
hypothetical protein, unknown function
— OG6
LmjF.15.0560
hypothetical protein, conserved
— OG6
LmjF.10.1080
Eukaryotic translation initiation factor 4 ga
— OG6
LmjF.15.1010
glutamate dehydrogenase
— OG6
LmjF.13.0690
PSP1 C-terminal conserved region, putative
— OG6
LmjF.09.0940
translation-associated element 2, putative
— OG6
LmjF.28.0230
hypothetical protein, unknown function
— OG6
LmjF.04.0570
DENN (AEX-3) domain containing protein, putat
— OG6
LmjF.04.0030
cAMP-specific phosphodiesterase, putative
— OG6
LmjF.21.0910
Aminoacyl-tRNA editing domain containing prot
— OG6
LmjF.08.0630
hypothetical protein, unknown function
— OG6
LmjF.07.0550
hypothetical protein, conserved
— OG6
LmjF.15.1300
ubiquitin hydrolase, putative
— OG6
LmjF.09.1180
hypothetical protein, conserved
— OG6
LmjF.09.0980
hypothetical protein, conserved
— OG6
LmjF.08.0910
Beta-lactamase superfamily domain containing
— OG6
LmjF.28.2730
hypothetical protein, conserved
— OG6
LmjF.11.0730
hypothetical protein, conserved
— OG6
LmjF.22.1500
ATP-dependent DEAD/H RNA helicase, putative
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.