LmjF.30.2440

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_147272 OG7: OG7_0043245 161 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 161 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmjF.14.0570
WD domain, G-beta repeat, putative
— Both
LmjF.15.0700
hypothetical protein, conserved
— Both
LmjF.22.1500
ATP-dependent DEAD/H RNA helicase, putative
— OG6
LmjF.08.0510 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
LmjF.27.0820
parallel beta-helix repeat, putative
— Both
LmjF.04.0350
hypothetical protein, conserved
— Both
LmjF.16.0730 ⚠
ubiquitin hydrolase, putative
— Both
LmjF.15.0920
protein phosphatase 2A regulatory subunit, pu
— Both
LmjF.01.0430 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LmjF.23.0120 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LmjF.18.1450
Protein of unknown function (DUF3648), putati
— Both
LmjF.29.2670
Serine/threonine-protein kinase NEK6, putativ
— OG6
LmjF.06.0190
hypothetical protein, conserved
— Both
LmjF.13.1120 ⚠
DNA-directed RNA polymerase I subunit, putati
— Both
LmjF.25.1315 ⚠
DNA-directed RNA polymerase I subunit RPB10,
— Both
LmjF.17.0170 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.34.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmjF.32.0760 ⚠
cyclin 9, putative
— OG7
LmjF.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmjF.36.6770 ⚠
beta adaptin, putative
— OG7
LmjF.06.0500 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmjF.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.21.0820 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LmjF.11.0990 ⚠
adaptin-related protein-like protein
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.30.1200 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.21.0400 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LmjF.24.0620 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LmjF.31.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmjF.30.2630 ⚠
replication factor C, subunit 2, putative
— OG7
LmjF.24.0990 ⚠
replication factor C, subunit 1, putative
— OG7
LmjF.33.1930 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmjF.27.0550 ⚠
replication factor C, subunit 4, putative
— OG7
LmjF.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LmjF.35.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmjF.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmjF.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmjF.09.1170 ⚠
hypothetical protein, conserved
— OG7
LmjF.14.1170 ⚠
ras-like small GTPases, putative
— OG7
LmjF.35.4260 ⚠
predicted zinc finger protein
— OG7
LmjF.35.3500 ⚠
zinc finger protein, putative
— OG7
LmjF.34.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.32.1400 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LmjF.23.1380 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LmjF.26.1260 ⚠
hypothetical protein, unknown function
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.