LmjF.01.0350

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_157997 OG7: OG7_0051936 56 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 56 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.36.4320 ⚠
predicted C2 domain protein
— OG7
LmjF.33.2560
Unc104-like kinesin, putative
— OG6
LmjF.35.1620
Concanavalin A-like lectin/glucanases superfa
— Both
LmjF.20.1100
MORN repeat-containing protein
— Both
LmjF.10.0330
hypothetical protein, conserved
— Both
LmjF.09.1510
hypothetical protein, conserved
— Both
LmjF.01.0430 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LmjF.18.1130 ⚠
Ras-related protein Rab5A, putative
— OG6
LmjF.13.0220 ⚠
ras-related protein RAB5B, putative
— OG6
LmjF.21.1680 ⚠
pumillio protein 3, putative
— OG7
LmjF.20.1370 ⚠
pumilio protein 9, putative
— OG7
LmjF.06.0050 ⚠
pumilio/PUF RNA binding protein 5, putative
— OG7
LmjF.20.1365 ⚠
pumillio protein 9, putative
— OG7
LmjF.36.0050 ⚠
PUF1, putative
— OG7
LmjF.08.0110
hypothetical protein, unknown function
— Both
LmjF.25.1820
hypothetical protein, conserved
— OG7
LmjF.12.0380 ⚠
pumillio protein 4, putative
— OG7
LmjF.32.0760 ⚠
cyclin 9, putative
— OG7
LmjF.30.2630 ⚠
replication factor C, subunit 2, putative
— OG7
LmjF.24.0990 ⚠
replication factor C, subunit 1, putative
— OG7
LmjF.34.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.27.0550 ⚠
replication factor C, subunit 4, putative
— OG7
LmjF.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmjF.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmjF.35.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.34.3280 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LmjF.34.2150 ⚠
eukaryotic translation initiation factor 2-al
— OG7
LmjF.35.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmjF.36.5760
Rab3 GTPase-activating protein regulatory sub
— Both
LmjF.18.1420 ⚠
pumilio protein 2, putative
— Both
LmjF.18.0280
hypothetical protein, conserved
— Both
LmjF.33.1150 ⚠
pumilio protein 6, putative
— Both
LmjF.32.3210
Miro-like protein, putative
— Both
LmjF.36.0590
Eukaryotic translation initiation factor 4E t
— Both
LmjF.30.3740
ribosomal P protein AGP2beta-1, putative
— Both
LmjF.35.2180
hypothetical protein, conserved
— Both
LmjF.35.3360
Putative death-receptor fusion protein (DUF24
— Both
LmjF.20.1090 ⚠
hypothetical protein, conserved
— Both
LmjF.21.1130
hypothetical protein, conserved
— Both
LmjF.26.1650
hypothetical protein, conserved
— Both
LmjF.28.2490
hypothetical protein, conserved
— Both
LmjF.13.1120 ⚠
DNA-directed RNA polymerase I subunit, putati
— Both
LmjF.36.4330 ⚠
predicted C2 domain protein
— Both
LmjF.15.1300 ⚠
ubiquitin hydrolase, putative
— Both
LmjF.36.5640 ⚠
Cyclin 12, L-type
— Both
LmjF.30.2440
hypothetical protein, conserved
— Both
LmjF.31.1710
hypothetical protein, conserved
— Both
LmjF.19.0650
hypothetical protein, conserved
— Both
LmjF.11.0060 ⚠
eukaryotic translation initiation factor 2-al
— Both
LmjF.29.1460
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.