LmjF.20.1185

calpain-like cysteine peptidase, putative
Leishmania major strain Friedlin OG6: OG6_127587 OG7: OG7_0001161 127 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 127 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.08.0220 ⚠
ubiquitin-activating enzyme-like protein
— OG6
LmjF.11.0630 ⚠
metallo-peptidase, Clan MF, Family M17
— OG6
LmjF.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— OG6
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG6
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG6
LmjF.35.2940 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG6
LmjF.35.0030 ⚠
pyruvate kinase
— OG6
LmjF.26.0310 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG6
LmjF.34.3670 ⚠
vacuolar ATP synthase catalytic subunit A, pu
— OG6
LmjF.19.0650 ⚠
hypothetical protein, conserved
— OG6
LmjF.18.1320 ⚠
hypothetical protein, conserved
— OG6
LmjF.33.1910 ⚠
ribosome assembly protein RRB1, putative
— OG6
LmjF.25.1980 ⚠
hypothetical protein, conserved
— OG6
LmjF.13.0430 ⚠
Flagellar radial spoke protein 4/6
— OG6
LmjF.32.2910 ⚠
ubiquitin hydrolase, putative
— OG6
LmjF.30.0760 ⚠
hypothetical protein, conserved
— OG6
LmjF.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— OG6
LmjF.28.2770 ⚠
heat-shock protein hsp70, putative
— OG6
LmjF.28.2820 ⚠
heat shock protein 70, putative
— OG6
LmjF.28.2780 ⚠
heat-shock protein hsp70, putative
— OG6
LmjF.26.1240 ⚠
heat shock protein 70-related protein
— OG6
LmjF.35.3360 ⚠
Putative death-receptor fusion protein (DUF24
— OG6
LmjF.27.1940 ⚠
cdc2-related kinase 9
— OG6
LmjF.36.0970 ⚠
hypothetical protein, conserved
— OG6
LmjF.23.1680 ⚠
Inositol hexakisphosphate, putative
— OG6
LmjF.28.0825 ⚠
RNA binding protein rbp16, putative
— OG6
LmjF.24.0300 ⚠
hypothetical protein, conserved
— OG6
LmjF.36.5760 ⚠
Rab3 GTPase-activating protein regulatory sub
— OG6
LmjF.36.5640 ⚠
Cyclin 12, L-type
— OG6
LmjF.28.2730 ⚠
hypothetical protein, conserved
— OG6
LmjF.24.1220 ⚠
RNA-binding protein 38, putative
— OG6
LmjF.30.2730 ⚠
Stabilization of polarity axis, putative
— OG6
LmjF.05.1080 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG6
LmjF.22.0590 ⚠
Uncharacterised protein family UPF0066, putat
— OG6
LmjF.15.0280 ⚠
ribonucleoprotein p18, mitochondrial precurso
— OG6
LmjF.15.1010 ⚠
glutamate dehydrogenase
— OG6
LmjF.09.0230 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG6
LmjF.09.0740 ⚠
ubiquitin ligase, putative
— OG6
LmjF.22.0650 ⚠
guide RNA associated protein, GAP2, putative
— OG6
LmjF.15.1480 ⚠
cAMP specific phosphodiesterase, putative
— OG6
LmjF.06.0810 ⚠
hypothetical protein, unknown function
— OG6
LmjF.26.1900 ⚠
hypothetical protein, conserved
— OG6
LmjF.10.1200 ⚠
hypothetical protein, conserved
— OG6
LmjF.25.2300 ⚠
Leucine Rich repeats (2 copies), putative
— OG6
LmjF.18.0070 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— OG6
LmjF.36.4230 ⚠
paraflagellar rod component, putative
— OG6
LmjF.35.0700 ⚠
vacuolar ATP synthase subunit d, putative
— OG6
LmjF.30.0560 ⚠
hypothetical protein, conserved
— OG6
LmjF.13.0940 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— OG6
LmjF.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.