LmjF.21.1295

Ring finger domain containing protein, putative
Leishmania major strain Friedlin OG6: OG6_199865 OG7: OG7_0000431 39 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 39 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.13.0130 ⚠
Kinesin-13 2
— OG7
LmjF.24.0640 ⚠
Kinesin-13 3, putative
— OG7
LmjF.31.0290 ⚠
Kinesin-13 4, putative
— OG7
LmjF.13.1610 ⚠
Kinesin-13 5, putative
— OG7
LmjF.01.0030 ⚠
Kinesin-13 1, putative
— OG7
LmjF.29.1950 ⚠
protein farnesyltransferase alpha subunit, pu
— OG7
LmjF.36.4370 ⚠
ubiquitin protein ligase, putative
— OG7
LmjF.34.0310 ⚠
tRNA pseudouridine synthase, putative
— OG7
LmjF.32.1090 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.23.0490 ⚠
5'-AMP-activated protein kinase subunit beta,
— OG7
LmjF.05.0610 ⚠
Surp module, putative
— OG7
LmjF.33.2650 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.3980 ⚠
Gar1/Naf1 RNA binding region, putative
— OG7
LmjF.34.3960 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.03.0060 ⚠
Met-10+ like-protein, putative
— OG7
LmjF.34.1110 ⚠
Shwachman-Bodian-Diamond syndrome (SBDS) prot
— OG7
LmjF.16.0310 ⚠
Met-10+ like-protein, putative
— OG7
LmjF.06.1130 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.0360 ⚠
ubiquitin activating enzyme, putative
— OG7
LmjF.30.1980 ⚠
C2H2 type zinc-finger (2 copies), putative
— OG7
LmjF.18.0650 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
LmjF.20.0940 ⚠
cyclophilin 15, putative
— OG7
LmjF.26.1280 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.1150 ⚠
pumilio protein 6, putative
— OG7
LmjF.18.1420 ⚠
pumilio protein 2, putative
— OG7
LmjF.20.1370 ⚠
pumilio protein 9, putative
— OG7
LmjF.06.0050 ⚠
pumilio/PUF RNA binding protein 5, putative
— OG7
LmjF.20.1365 ⚠
pumillio protein 9, putative
— OG7
LmjF.36.0050 ⚠
PUF1, putative
— OG7
LmjF.12.0380 ⚠
pumillio protein 4, putative
— OG7
LmjF.33.1910 ⚠
ribosome assembly protein RRB1, putative
— OG7
LmjF.19.1020 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LmjF.30.3360 ⚠
calmodulin-related protein, putative
— OG7
LmjF.30.1550 ⚠
pseudouridine synthase A-like protein, putati
— OG7
LmjF.35.2450 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.32.2390 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.2980 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.0420 ⚠
pseudouridylate synthase-like protein
— OG7
LmjF.21.1680 ⚠
pumillio protein 3, putative
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.