LmjF.35.4470

Co-chaperone protein P23
Leishmania major strain Friedlin OG6: OG6_101574 OG7: OG7_0005368 132 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 132 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.32.3650 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmjF.18.1660 ⚠
gamma-glutamylcysteine synthetase, putative
— Both
LmjF.32.3680 ⚠
3-hydroxyisobutyryl-coenzyme A hydrolase, put
— Both
LmjF.14.1160 ⚠
enolase
— Both
LmjF.05.0970 ⚠
3-mercaptopyruvate sulfurtransferase
— Both
LmjF.29.1310 ⚠
carnitine/choline acetyltransferase, putative
— Both
LmjF.30.2610 ⚠
RNA-binding protein, putative
— OG6
LmjF.28.1370 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LmjF.24.0370 ⚠
aspartate aminotransferase, putative
— Both
LmjF.35.0820 ⚠
aspartate aminotransferase, putative
— Both
LmjF.34.0210 ⚠
CS domain containing protein, putative
— Both
LmjF.18.0290 ⚠
dephospho-CoA kinase, putative
— Both
LmjF.28.1110 ⚠
WD domain, G-beta repeat, putative
— Both
LmjF.32.2070 ⚠
phosphopantetheine adenylyltransferase, putat
— Both
LmjF.32.0910 ⚠
Alpha/beta hydrolase family, putative
— Both
LmjF.28.1140 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LmjF.23.1480 ⚠
alanine racemase, putative
— Both
LmjF.22.0320 ⚠
SEP domain containing protein, putative
— Both
LmjF.34.3780 ⚠
phosphomannomutase-like protein
— Both
LmjF.31.0140 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
LmjF.28.2070 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
LmjF.33.0960 ⚠
nicotinate phosphoribosyltransferase, putativ
— Both
LmjF.33.2810 ⚠
transcription elongation factor-like protein
— Both
LmjF.01.0220 ⚠
cyclophilin 12, putative
— OG6
LmjF.27.0720 ⚠
UBA/TS-N domain containing protein, putative
— Both
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmjF.31.0290 ⚠
Kinesin-13 4, putative
— OG7
LmjF.13.1610 ⚠
Kinesin-13 5, putative
— OG7
LmjF.01.0030 ⚠
Kinesin-13 1, putative
— OG7
LmjF.13.0130 ⚠
Kinesin-13 2
— OG7
LmjF.32.3660 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmjF.32.3670 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmjF.36.0540 ⚠
ubiquitin-like protein, putative
— OG7
LmjF.25.1020 ⚠
dehydrogenase-like protein
— OG7
LmjF.19.1540 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LmjF.22.0310 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LmjF.28.1340 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LmjF.28.1350 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.28.1360 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.28.1380 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.17.1150 ⚠
5'-3' exoribonuclease B, putative
— OG7
LmjF.19.1480 ⚠
eukaryotic translation initiation factor-like
— OG7
LmjF.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmjF.24.0210 ⚠
transcription elongation factor, putative
— OG7
LmjF.30.0450 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LmjF.01.0210 ⚠
CUE domain/Domain of unknown function (DUF177
— OG7
LmjF.13.0730 ⚠
ubiquitin-like protein
— OG7
LmjF.07.0050 ⚠
alpha-adaptin-like protein
— OG7
LmjF.19.1500 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.