LmjF.13.1100

leucyl-tRNA synthetase, putative

Leishmania major strain Friedlin OG6: OG6_101014 OG7: OG7_0005523 101 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 101 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LmjF.21.0810 methionyl-tRNA synthetase	—	OG6 Tb927.10.1500 ↔ Tb927.11.3730 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.11.3730 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007991	Both
LmjF.36.5620 isoleucyl-tRNA synthetase, putative	—	OG6 Tb927.10.9190 ↔ Tb927.11.3730 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.11.3730 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004705	Both
LmjF.29.0060 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_010724 OG6 Tb927.11.3730 ↔ Tb927.3.5580 OG7 Tb927.11.3730 ↔ Tb927.3.5580 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010724	Both
LmjF.36.3840 glycyl tRNA synthetase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_009222 OG6 Tb927.11.3730 ↔ Tb927.11.9640 OG7 Tb927.11.3730 ↔ Tb927.11.9640 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_009222	Both
LmjF.30.3130 valyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003345 OG6 Tb927.11.3730 ↔ Tb927.6.4480 OG7 Tb927.11.3730 ↔ Tb927.6.4480 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003345	Both
LmjF.14.1370 ⚠ tyrosyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_010624 OG6 Tb927.11.3730 ↔ Tb927.7.3620 OG7 Tb927.11.3730 ↔ Tb927.7.3620 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010624	Both
LmjF.23.0300 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG7 Tb927.11.3730 ↔ Tb927.3.5580 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010724	OG7
LmjF.22.0470 ⚠ Putative tRNA binding domain containing prote	—	OG7 Tb927.11.3730 ↔ Tb927.7.3620 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010624	OG7
LmjF.16.1130 ⚠ tyrosyl or methionyl-tRNA synthetase-like pro	—	OG7 Tb927.11.3730 ↔ Tb927.7.3620 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010624	OG7
LmjF.24.1170 hypothetical protein, conserved	—	OG6 TCSYLVIO_001462 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001462 ↔ TCSYLVIO_003028	Both
LmjF.15.0040 Possible lysine decarboxylase, putative	—	OG6 TCSYLVIO_002403 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_002403 ↔ TCSYLVIO_003028	Both
LmjF.06.0880 acyl-coenzyme a dehydrogenase, putative	—	OG6 TCSYLVIO_001861 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001861 ↔ TCSYLVIO_003028	Both
LmjF.31.3090 metallo-peptidase, Clan ME, Family M16	—	OG6 TCSYLVIO_002764 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_002764 ↔ TCSYLVIO_003028	Both
LmjF.31.2980 hypothetical protein, conserved	—	OG6 TCSYLVIO_002771 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_002771 ↔ TCSYLVIO_003028	Both
LmjF.22.0140 hypothetical protein, conserved	—	OG6 TCSYLVIO_001150 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001150 ↔ TCSYLVIO_003028	Both
LmjF.34.2340 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003867 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003867	Both
LmjF.36.2420 serine peptidase, Clan SC, Family S9B	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007536 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007536	Both
LmjF.25.0170 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_005414 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_005414	Both
LmjF.17.0350 ⚠ dihydrouridine synthase (Dus), putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_009102	Both
LmjF.30.3300 UV excision repair RAD23-like protein	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003361 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003361	Both
LmjF.06.0340 ⚠ serine peptidase, clan SC, family S9A-like pr	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_006546 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_006546	Both
LmjF.36.2170 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004998 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004998	Both
LmjF.35.1050 calcium/calmodulin-dependent protein kinase,	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_005149	OG6
LmjF.30.0610 nitrate reductase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003124	OG6
LmjF.35.3260 Peroxin 19	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_005818 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_005818	Both
LmjF.30.2320 SET domain containing protein, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003268 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003268	Both
LmjF.26.0320 ⚠ C-1-tetrahydrofolate synthase, cytoplasmic, p	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003291	OG6
LmjF.30.3440 ⚠ DNA ligase I, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003375	Both
LmjF.20.1710 tRNA (Uracil-5-)-methyltransferase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_008409 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_008409	Both
LmjF.29.1580 XPC-binding domain containing protein, putati	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004322 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004322	Both
LmjF.30.0630 histidyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003126 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003126	Both
LmjF.14.1320 ⚠ serine hydroxymethyltranferase (SHMT-S)	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010621	Both
LmjF.35.0390 hypothetical protein, conserved	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_005084 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_005084	Both
LmjF.03.0200 delta-1-pyrroline-5-carboxylate dehydrogenase	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004515 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004515	Both
LmjF.28.2370 ⚠ serine hydroxymethyltransferase (SHMT-L)	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010621	Both
LmjF.27.0380 Nuclear pore complex protein 158	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007387 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007387	Both
LmjF.14.0450 ⚠ N-terminal conserved domain of Nudc./CS domai	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_010327 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010327	Both
LmjF.36.0130 PUB domain containing protein, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_009932 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_009932	Both
LmjF.36.0070 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003496	OG6
LmjF.27.2390 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003496	OG6
LmjF.25.2410 hypothetical protein, conserved	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_010323 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010323	Both
LmjF.25.2120 eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_006404	Both
LmjF.29.2540 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004998 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004998	Both
LmjF.30.3420 T-complex protein 11, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003373 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003373	Both
LmjF.14.1360 inositol-3-phosphate synthase	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007453	Both
LmjF.36.6070 ⚠ disgorgin, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004663 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004663	Both
LmjF.34.3750 hypothetical protein, conserved	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003737 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003737	Both
LmjF.25.0870 ⚠ Atypical serine/threonine protein kinase BUD3	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007401 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007401	Both
LmjF.23.0110 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007603	Both
LmjF.34.0330 ⚠ deoxyhypusine synthase	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007258	Both

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