LmjF.13.1100

leucyl-tRNA synthetase, putative
Leishmania major strain Friedlin OG6: OG6_101014 OG7: OG7_0005523 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.21.0810
methionyl-tRNA synthetase
— Both
LmjF.36.5620
isoleucyl-tRNA synthetase, putative
— Both
LmjF.29.0060 ⚠
tryptophanyl-tRNA synthetase, putative
— Both
LmjF.36.3840
glycyl tRNA synthetase, putative
— Both
LmjF.30.3130
valyl-tRNA synthetase, putative
— Both
LmjF.14.1370 ⚠
tyrosyl-tRNA synthetase, putative
— Both
LmjF.23.0300 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LmjF.22.0470 ⚠
Putative tRNA binding domain containing prote
— OG7
LmjF.16.1130 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— OG7
LmjF.24.1170
hypothetical protein, conserved
— Both
LmjF.15.0040
Possible lysine decarboxylase, putative
— Both
LmjF.06.0880
acyl-coenzyme a dehydrogenase, putative
— Both
LmjF.31.3090
metallo-peptidase, Clan ME, Family M16
— Both
LmjF.31.2980
hypothetical protein, conserved
— Both
LmjF.22.0140
hypothetical protein, conserved
— Both
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LmjF.36.2420
serine peptidase, Clan SC, Family S9B
— Both
LmjF.25.0170 ⚠
cleavage and polyadenylation specificity fact
— Both
LmjF.17.0350 ⚠
dihydrouridine synthase (Dus), putative
— Both
LmjF.30.3300
UV excision repair RAD23-like protein
— Both
LmjF.06.0340 ⚠
serine peptidase, clan SC, family S9A-like pr
— Both
LmjF.36.2170 ⚠
NOL1/NOP2/sun family, putative
— Both
LmjF.35.1050
calcium/calmodulin-dependent protein kinase,
— OG6
LmjF.30.0610
nitrate reductase, putative
— OG6
LmjF.35.3260
Peroxin 19
— Both
LmjF.30.2320
SET domain containing protein, putative
— Both
LmjF.26.0320 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG6
LmjF.30.3440 ⚠
DNA ligase I, putative
— Both
LmjF.20.1710
tRNA (Uracil-5-)-methyltransferase, putative
— Both
LmjF.29.1580
XPC-binding domain containing protein, putati
— Both
LmjF.30.0630
histidyl-tRNA synthetase, putative
— Both
LmjF.14.1320 ⚠
serine hydroxymethyltranferase (SHMT-S)
— Both
LmjF.35.0390
hypothetical protein, conserved
— Both
LmjF.03.0200
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
LmjF.28.2370 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LmjF.27.0380
Nuclear pore complex protein 158
— Both
LmjF.14.0450 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
LmjF.36.0130
PUB domain containing protein, putative
— Both
LmjF.36.0070 ⚠
stress-inducible protein STI1 homolog
— OG6
LmjF.27.2390 ⚠
TPR-repeat protein, putative
— OG6
LmjF.25.2410
hypothetical protein, conserved
— Both
LmjF.25.2120
eukaryotic translation initiation factor 3 su
— Both
LmjF.29.2540 ⚠
NOL1/NOP2/sun family, putative
— Both
LmjF.30.3420
T-complex protein 11, putative
— Both
LmjF.14.1360
inositol-3-phosphate synthase
— Both
LmjF.36.6070 ⚠
disgorgin, putative
— Both
LmjF.34.3750
hypothetical protein, conserved
— Both
LmjF.25.0870 ⚠
Atypical serine/threonine protein kinase BUD3
— Both
LmjF.23.0110
GDP-mannose pyrophosphorylase
— Both
LmjF.34.0330 ⚠
deoxyhypusine synthase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.