LmjF.17.0350

dihydrouridine synthase (Dus), putative
Leishmania major strain Friedlin OG6: OG6_101202 OG7: OG7_0002064 217 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 217 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.30.3440 ⚠
DNA ligase I, putative
— Both
LmjF.29.1970 ⚠
hypothetical protein, unknown function
— OG7
LmjF.36.0180 ⚠
elongation factor 2
— OG7
LmjF.27.0940 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LmjF.16.0390 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LmjF.23.1640 ⚠
Galactose oxidase, central domain containing
— OG7
LmjF.05.0970 ⚠
3-mercaptopyruvate sulfurtransferase
— OG7
LmjF.20.0790 ⚠
tubulin-tyrosine ligase, putative
— OG7
LmjF.29.0260 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LmjF.03.0160 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LmjF.33.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LmjF.30.3080 ⚠
homoserine kinase
— OG7
LmjF.16.0380 ⚠
tubulin tyrosine ligase, putative
— OG7
LmjF.35.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmjF.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmjF.30.2280 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.08.0310 ⚠
Isochorismatase family, putative
— OG7
LmjF.32.2930 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.08.0320 ⚠
mitochondrial associated ribonuclease, putati
— OG7
LmjF.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmjF.08.0300 ⚠
Isochorismatase family, putative
— OG7
LmjF.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.12.0060 ⚠
ribonuclease mar1
— OG7
LmjF.16.0540 ⚠
aspartate carbamoyltransferase, putative
— OG7
LmjF.05.0740 ⚠
Vta1 like, putative
— OG7
LmjF.26.2080 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.2090 ⚠
hypothetical protein, unknown function
— OG7
LmjF.25.2080 ⚠
elongation factor 2-like protein
— OG7
LmjF.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmjF.34.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.30.2270 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.4540 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmjF.35.3260 ⚠
Peroxin 19
— OG7
LmjF.32.1090 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.33.3050 ⚠
tyrosyl-DNA phosphodiesterase 1
— OG7
LmjF.34.2750 ⚠
methyltransferase-like protein
— OG7
LmjF.33.1610 ⚠
cytosolic nonspecific dipeptidase, putative
— OG7
LmjF.31.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.31.1890 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LmjF.34.3430 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmjF.10.0570 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LmjF.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmjF.35.3060 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmjF.36.0190 ⚠
elongation factor 2
— OG7
LmjF.23.0550 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmjF.32.2200 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
LmjF.27.2630 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG7
LmjF.29.1270 ⚠
Heat shock protein 100 kDa
— OG7
LmjF.10.0560 ⚠
zinc binding dehydrogenase-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.