LmjF.14.1370

tyrosyl-tRNA synthetase, putative
Leishmania major strain Friedlin OG6: OG6_101224 OG7: OG7_0002829 150 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 150 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.21.0810 ⚠
methionyl-tRNA synthetase
— +2 more Both
LmjF.30.3130 ⚠
valyl-tRNA synthetase, putative
— Both
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.36.5620 ⚠
isoleucyl-tRNA synthetase, putative
— Both
LmjF.13.1100 ⚠
leucyl-tRNA synthetase, putative
— Both
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.35.0380 ⚠
thioredoxin, putative
— OG7
LmjF.36.3840 ⚠
glycyl tRNA synthetase, putative
— OG7
LmjF.11.0100 ⚠
seryl-tRNA synthetase
— OG7
LmjF.34.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmjF.34.3430 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmjF.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— OG7
LmjF.18.0550 ⚠
hypothetical protein, conserved
— OG7
LmjF.16.1425 ⚠
Paraflagellar rod protein 2-3
— OG7
LmjF.16.1427 ⚠
Paraflagellar rod protein 2-2
— OG7
LmjF.16.1430 ⚠
Paraflagellar rod protein 2-1
— OG7
LmjF.33.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LmjF.03.0160 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LmjF.21.0910 ⚠
Aminoacyl-tRNA editing domain containing prot
— OG7
LmjF.30.1380 ⚠
amidohydrolase, putative
— OG7
LmjF.30.0730 ⚠
co-chaperone GrpE, putative
— OG7
LmjF.35.1420 ⚠
peroxisome targeting signal 1 receptor, putat
— OG7
LmjF.23.0300 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LmjF.30.0735 ⚠
heat shock protein grpe
— OG7
LmjF.17.0980 ⚠
Mak10 subunit, NatC N(alpha)-terminal acetylt
— OG7
LmjF.27.1310 ⚠
arginyl-tRNA synthetase, putative
— OG7
LmjF.11.0630 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.17.1130 ⚠
NOL1/NOP2/sun family, putative
— OG7
LmjF.20.1560 ⚠
amidohydrolase, putative
— OG7
LmjF.18.1110 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LmjF.31.1130 ⚠
amidohydrolase, putative
— OG7
LmjF.20.1570 ⚠
amidohydrolase, putative
— OG7
LmjF.36.4040 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.1120 ⚠
hypothetical protein, conserved
— OG7
LmjF.07.0960 ⚠
hypothetical protein, conserved
— OG7
LmjF.31.1930 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.24.1340 ⚠
translation initiation factor IF-2, putative
— OG7
LmjF.36.4670 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.0470 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LmjF.34.1140 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.18.1220 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LmjF.31.0230 ⚠
hypothetical protein, conserved
— OG7
LmjF.04.1080 ⚠
Transcriptional repressor TCF25, putative
— OG7
LmjF.30.3240 ⚠
glutamyl-tRNA synthetase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.