LmjF.30.0610

nitrate reductase, putative
Leishmania major strain Friedlin OG6: OG6_133565 OG7: OG7_0002230 83 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 83 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.30.2600 ⚠
formate--tetrahydrofolate ligase
— OG6
LmjF.22.0140
hypothetical protein, conserved
— OG6
LmjF.31.2980
hypothetical protein, conserved
— OG6
LmjF.35.0350
hypothetical protein, conserved
— OG6
LmjF.35.2730
acyl-CoA dehydrogenase, putative
— OG6
LmjF.29.2110
UDP-glucose:glycoprotein glucosyltransferase,
— OG6
LmjF.19.0800
ABC transport system ATP-binding protein, put
— OG6
LmjF.20.1150
Pre-mRNA-splicing factor 38, putative
— OG6
LmjF.18.0090
alpha glucosidase II subunit, putative
— OG6
LmjF.35.4550
hypothetical protein, conserved
— OG6
LmjF.33.1380 ⚠
mitogen-activated protein kinase 11, putative
— OG6
LmjF.13.1100
leucyl-tRNA synthetase, putative
— OG6
LmjF.18.0880
cyclosporin 16, putative
— OG6
LmjF.20.0250 ⚠
deoxyhypusine synthase, putative
— OG6
LmjF.14.1370
tyrosyl-tRNA synthetase, putative
— OG6
LmjF.30.1120
importin alpha, putative
— OG6
LmjF.21.0810
methionyl-tRNA synthetase
— OG6
LmjF.34.0330 ⚠
deoxyhypusine synthase
— OG6
LmjF.23.0110
GDP-mannose pyrophosphorylase
— OG6
LmjF.25.0870
Atypical serine/threonine protein kinase BUD3
— OG6
LmjF.34.3750
hypothetical protein, conserved
— OG6
LmjF.22.0300
hypothetical protein, conserved
— OG6
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG6
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG6
LmjF.32.3980
Gar1/Naf1 RNA binding region, putative
— OG6
LmjF.28.0450
DIS3-like exonuclease, putative
— OG6
LmjF.22.1540
alanyl-tRNA synthetase, putative
— OG6
LmjF.05.0820
hypothetical protein, conserved
— OG6
LmjF.33.2610
Mitochondrial-processing peptidase subunit al
— OG6
LmjF.22.1240
translation initiation factor IF-2, putative
— OG6
LmjF.05.0970
3-mercaptopyruvate sulfurtransferase
— OG6
LmjF.18.0010
kinetoplast polyadenylation/uridylation facto
— OG6
LmjF.36.6070
disgorgin, putative
— OG6
LmjF.13.0160
protein kinase A regulatory subunit
— OG6
LmjF.06.0950
glucosamine-fructose-6-phosphate aminotransfe
— OG6
LmjF.31.2600
calreticulin, putative
— OG6
LmjF.01.0830 ⚠
metallo-peptidase, Clan MA(E), Family M3
— OG6
LmjF.02.0740 ⚠
dipeptylcarboxypeptidase, putative
— OG6
LmjF.27.2660 ⚠
peptidyl dipeptidase, putative
— OG6
LmjF.26.1570 ⚠
thimet oligopeptidase, putative
— OG6
LmjF.11.0530
hypothetical protein, conserved
— OG6
LmjF.26.1000
glucosidase II beta subunit-like protein, put
— OG6
LmjF.19.1440 ⚠
mitogen-activated protein kinase 4
— OG6
LmjF.20.1710
tRNA (Uracil-5-)-methyltransferase, putative
— OG6
LmjF.26.0320 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG6
LmjF.30.2320
SET domain containing protein, putative
— OG6
LmjF.29.0060
tryptophanyl-tRNA synthetase, putative
— OG6
LmjF.25.0750
protein phosphatase 2C, putative
— OG6
LmjF.35.1050
calcium/calmodulin-dependent protein kinase,
— OG6
LmjF.36.2170 ⚠
NOL1/NOP2/sun family, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.