LmjF.25.0750

protein phosphatase 2C, putative
Leishmania major strain Friedlin OG6: OG6_142542 OG7: OG7_0000783 20 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 20 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.35.0380
thioredoxin, putative
— OG6
LmjF.36.2360
tyrosine aminotransferase
— OG6
LmjF.33.1380 ⚠
mitogen-activated protein kinase 11, putative
— OG6
LmjF.36.3910
S-adenosylhomocysteine hydrolase
— OG6
LmjF.17.1410
zinc-finger protein ZPR1, putative
— OG6
LmjF.07.0805
N-acetylglucosamine-phosphate mutase, putativ
— OG6
LmjF.19.1440 ⚠
mitogen-activated protein kinase 4
— OG6
LmjF.33.2610
Mitochondrial-processing peptidase subunit al
— OG6
LmjF.05.0970
3-mercaptopyruvate sulfurtransferase
— OG6
LmjF.33.2300
udp-glc 4'-epimerase, putative
— OG6
LmjF.17.0250 ⚠
cystathionine beta-synthase
— OG6
LmjF.13.0160
protein kinase A regulatory subunit
— OG6
LmjF.01.0830 ⚠
metallo-peptidase, Clan MA(E), Family M3
— OG6
LmjF.02.0740 ⚠
dipeptylcarboxypeptidase, putative
— OG6
LmjF.27.2660 ⚠
peptidyl dipeptidase, putative
— OG6
LmjF.26.1570 ⚠
thimet oligopeptidase, putative
— OG6
LmjF.25.2430 ⚠
Xaa-Pro aminopeptidase, putative
— OG6
LmjF.02.0040 ⚠
Xaa-Pro aminopeptidase, putative
— OG6
LmjF.30.0610
nitrate reductase, putative
— OG6
LmjF.36.3590 ⚠
cysteine synthase
— OG6
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.