LmjF.21.0950

Programmed cell death protein 2, C-terminal putative domain containing protein, putative
Leishmania major strain Friedlin OG6: OG6_103161 OG7: OG7_0004545 82 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 82 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.07.0100 ⚠
metallo-peptidase, Clan ME, Family M16C
— Both
LmjF.08.0300 ⚠
Isochorismatase family, putative
— OG7
LmjF.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmjF.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.12.0060 ⚠
ribonuclease mar1
— OG7
LmjF.13.0870 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LmjF.21.0340 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LmjF.35.5310 ⚠
ribosome-interacting GTPase 2, putative
— OG7
LmjF.10.0570 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LmjF.18.1330 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— OG7
LmjF.35.3070 ⚠
hypothetical protein, conserved
— Both
LmjF.03.0750 ⚠
TatD related DNase, putative
— Both
LmjF.29.1100 ⚠
Ankyrin repeats (3 copies), putative
— Both
LmjF.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.22.1130 ⚠
Beta-lactamase superfamily domain containing
— Both
LmjF.22.1120 ⚠
Beta-lactamase superfamily domain containing
— Both
LmjF.35.3060 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LmjF.30.0520 ⚠
N-acetyltransferase B complex (NatB) non cata
— Both
LmjF.23.1630 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.26.2080 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.0140 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.18.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.04.0520 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LmjF.34.4280 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.03.0480 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LmjF.35.2670 ⚠
ankyrin repeat protein, putative
— OG7
LmjF.30.3260 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.17.0350 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.29.1970 ⚠
hypothetical protein, unknown function
— OG7
LmjF.36.0470 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LmjF.31.2020 ⚠
succinyl-diaminopimelate desuccinylase-like p
— Both
LmjF.34.1140 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.35.2340 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.29.0260 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LmjF.16.0380 ⚠
tubulin tyrosine ligase, putative
— OG7
LmjF.35.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmjF.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmjF.30.2280 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.08.0310 ⚠
Isochorismatase family, putative
— OG7
LmjF.32.2930 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.08.0320 ⚠
mitochondrial associated ribonuclease, putati
— Both
LmjF.26.0580 ⚠
Protein of unknown function (DUF525), putativ
— Both
LmjF.25.1730 ⚠
hypothetical protein, conserved
— Both
LmjF.24.0190 ⚠
hypothetical protein, conserved
— Both
LmjF.32.0890 ⚠
ethanolamine-phosphate cytidylyltransferase
— Both
LmjF.15.1170 ⚠
hypothetical protein, conserved
— Both
LmjF.03.0610 ⚠
kinase-like protein
— Both
LmjF.05.0970 ⚠
3-mercaptopyruvate sulfurtransferase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.