LmjF.03.0270

FYVE zinc finger/Apolipoprotein A1/A4/E domain containing protein, putative
Leishmania major strain Friedlin OG6: OG6_163591 OG7: OG7_0019980 110 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 110 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.28.1760 ⚠
Serine/threonine-protein kinase VPS15, putati
— OG7
LmjF.03.0480 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LmjF.32.1340 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmjF.30.1990 ⚠
cyclosome subunit-like protein
— OG7
LmjF.33.0140 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.14.0790 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.0490 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.1440 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LmjF.34.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmjF.25.1840 ⚠
General negative regulator of transcription s
— OG7
LmjF.20.1240 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LmjF.15.1200 ⚠
STE group serine/threonine-protein kinase, pu
— OG7
LmjF.30.2210 ⚠
endosomal trafficking protein RME-8, putative
— OG7
LmjF.27.2170 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.1510 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.1180 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LmjF.21.0800 ⚠
CCR4-NOT transcription complex subunit 1
— OG7
LmjF.09.0990 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LmjF.32.1470 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LmjF.29.2250 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.1970 ⚠
Nucleoporin NUP76
— OG7
LmjF.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.16.0780 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LmjF.36.3070 ⚠
fibrillarin
— OG7
LmjF.34.4280 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.26.1950 ⚠
microtubule-associated protein, putative
— OG7
LmjF.25.0170 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmjF.21.1020 ⚠
dynein arm light chain, putative
— OG7
LmjF.04.0550 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
LmjF.17.1150 ⚠
5'-3' exoribonuclease B, putative
— OG7
LmjF.36.1790 ⚠
5'-3' exoribonuclease D, putative
— OG7
LmjF.06.0260 ⚠
5'-3' exoribonuclease A, putative
— OG7
LmjF.19.0100 ⚠
fibrillarin, putative
— OG7
LmjF.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LmjF.31.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.36.2630 ⚠
protein kinase, putative
— OG7
LmjF.33.0280 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.6340 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.18.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.34.3430 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmjF.32.3970 ⚠
cAMP response protein 1, putative
— OG7
LmjF.32.0310 ⚠
intraflagellar transport protein 140, putativ
— OG7
LmjF.04.0520 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LmjF.20.0260 ⚠
Midasin, putative
— OG7
LmjF.24.1960 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.0940 ⚠
CAP-Gly domain containing protein, putative
— OG7
LmjF.18.0460 ⚠
tubulin-specific chaperone, putative
— OG7
LmjF.13.0270 ⚠
hypothetical protein, conserved
— OG7
LmjF.25.0610 ⚠
Regulatory-associated protein of TOR1
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.