LmjF.30.0710

CDC16, putative
Leishmania major strain Friedlin OG6: OG6_102501 OG7: OG7_0007209 61 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 61 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.04.0400
anaphase promoting complex, subunit 10-like p
— Both
LmjF.30.1990
cyclosome subunit-like protein
— Both
LmjF.12.0610 ⚠
TPR repeat, putative
— +2 more Both
LmjF.06.1160
hypothetical protein, conserved
— Both
LmjF.05.0410 ⚠
TPR repeat, putative
— +2 more Both
LmjF.32.0250
hypothetical protein, conserved
— Both
LmjF.32.1340
cleavage and polyadenylation specificity fact
— Both
LmjF.30.2210
endosomal trafficking protein RME-8, putative
— Both
LmjF.35.4010 ⚠
cAMP-dependent protein kinase catalytic subun
— OG6
LmjF.09.1220
AAA family ATPase, putative
— Both
LmjF.05.1080 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
LmjF.34.2450 ⚠
Sec7 domain containing protein, putative
— OG7
LmjF.34.2520 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.36.1000
intraflagellar transport protein 122, putativ
— Both
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LmjF.18.1080 ⚠
cAMP-dependent protein kinase catalytic subun
— OG6
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.16.0650 ⚠
RING-H2 zinc finger, putative
— OG7
LmjF.24.1610 ⚠
ring-box protein, putative
— OG7
LmjF.21.0023 ⚠
ring-box protein 1, putative
— OG7
LmjF.34.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmjF.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— OG7
LmjF.13.1470 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LmjF.35.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmjF.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmjF.29.1180
hypothetical protein, conserved
— Both
LmjF.35.4500 ⚠
anaphase promoting complex subunit protein, p
— Both
LmjF.27.2480
WD-repeat protein
— Both
LmjF.21.1330 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— Both
LmjF.17.0430
hypothetical protein, conserved
— Both
LmjF.07.0120 ⚠
Sec7 domain containing protein, putative
— Both
LmjF.05.0920
paraflagellar rod protein, putative
— Both
LmjF.19.1010
WD domain, G-beta repeat, putative
— Both
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— Both
LmjF.07.0480
Dynein heavy chain, N-terminal region 2, puta
— OG6
LmjF.23.0020
hypothetical protein, conserved
— Both
LmjF.21.1670
hypothetical protein, conserved
— Both
LmjF.04.0550
TPR repeat/Tetratricopeptide repeat, putative
— Both
LmjF.03.0970 ⚠
MORN repeat, putative
— Both
LmjF.35.3750
Cullin family, putative
— Both
LmjF.31.3110
Flagellum attachment zone protein 14
— Both
LmjF.05.0190
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— Both
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.