LmjF.21.1330

RecF/RecN/SMC N terminal domain/SMC proteins Flexible Hinge Domain, putative
Leishmania major strain Friedlin OG6: OG6_101113 OG7: OG7_0001761 217 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 217 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.28.2760 ⚠
gamma-tubulin complex component 3
— OG7
LmjF.33.1180 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LmjF.34.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmjF.08.1090 ⚠
histone deacetylase, putative
— OG7
LmjF.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LmjF.16.1350 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LmjF.28.1460 ⚠
Cell division control protein 48, putative
— OG7
LmjF.33.2070 ⚠
mitogen-activated protein kinase, putative
— OG7
LmjF.34.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmjF.27.0820 ⚠
parallel beta-helix repeat, putative
— OG7
LmjF.11.0370 ⚠
hypothetical protein, conserved
— OG7
LmjF.18.0830 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
LmjF.23.0120 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmjF.34.4290 ⚠
nucleolar protein family a, putative
— OG7
LmjF.08.0420 ⚠
hypothetical protein, conserved
— OG7
LmjF.04.0960 ⚠
UMP/CMP kinase, putative
— OG7
LmjF.06.0500 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.12.0190 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LmjF.34.2240 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
LmjF.36.1360 ⚠
adenylate kinase, putative
— OG7
LmjF.33.1110 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.2440 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.2410 ⚠
Cullin protein neddylation domain containing
— OG7
LmjF.36.5260 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
LmjF.36.6770 ⚠
beta adaptin, putative
— OG7
LmjF.21.1870 ⚠
histone deacetylase, putative
— OG7
LmjF.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmjF.36.5020 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0320 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0790 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0270 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LmjF.17.1150 ⚠
5'-3' exoribonuclease B, putative
— OG7
LmjF.35.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmjF.36.5240 ⚠
glycosyl hydrolase, putative
— OG7
LmjF.13.1470 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LmjF.16.1550 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.3060 ⚠
46 kD virulence factor
— OG7
LmjF.31.2970 ⚠
acetyl-CoA carboxylase
— OG7
LmjF.25.0290 ⚠
RNA-binding protein, putative
— OG7
LmjF.08.0510 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
LmjF.32.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmjF.23.0547 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.0840 ⚠
dynein arm light chain, putative
— OG7
LmjF.29.0140 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
LmjF.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmjF.33.1930 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmjF.34.1360 ⚠
Nucleoporin NUP225
— OG7
LmjF.15.0700 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.