LmjF.34.0360

DNA-directed RNA polymerase III subunit C1, putative
Leishmania major strain Friedlin OG6: OG6_100210 OG7: OG7_0001854 178 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 178 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.31.2970 ⚠
acetyl-CoA carboxylase
— Both
LmjF.08.0510 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
LmjF.19.0660 ⚠
DNA-directed RNA polymerases I and III subuni
— +2 more Both
LmjF.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— Both
LmjF.29.0140 ⚠
DNA-directed RNA polymerase II subunit 3, put
— +1 more Both
LmjF.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— +4 more Both
LmjF.31.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— +4 more Both
LmjF.25.0620 ⚠
RNA polymerase I second largest subunit, puta
— +1 more OG7
LmjF.33.1930 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmjF.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmjF.24.2100 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.1980 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.1720 ⚠
neurobeachin/beige protein, putative
— OG7
LmjF.14.1170 ⚠
ras-like small GTPases, putative
— OG7
LmjF.35.4260 ⚠
predicted zinc finger protein
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.35.2490 ⚠
hypothetical protein, conserved
— OG7
LmjF.25.1490 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
LmjF.36.4210 ⚠
WD domain, G-beta repeat/Utp21 specific WD40
— OG7
LmjF.32.2650 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.22.1630 ⚠
ccr4-not transcription complex subunit
— OG7
LmjF.11.0990 ⚠
adaptin-related protein-like protein
— OG7
LmjF.35.3500 ⚠
zinc finger protein, putative
— OG7
LmjF.17.0930 ⚠
formin, putative
— OG7
LmjF.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmjF.29.1830 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LmjF.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmjF.33.2700 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.21.1250 ⚠
adenylate kinase, putative
— OG7
LmjF.29.1900 ⚠
hypothetical protein, conserved
— OG7
LmjF.16.1220 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmjF.18.0830 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
LmjF.32.3170 ⚠
NADH dehydrogenase subunit NI8M, putative
— OG7
LmjF.27.0820 ⚠
parallel beta-helix repeat, putative
— OG7
LmjF.25.0940 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.1460 ⚠
Cell division control protein 48, putative
— OG7
LmjF.05.0330 ⚠
DNA replication licensing factor MCM8, putati
— OG7
LmjF.36.2790 ⚠
Flagellar Member 1
— OG7
LmjF.36.3530 ⚠
polyubiquitin, putative
— OG7
LmjF.32.0140 ⚠
Flagellum attachment zone protein 9
— OG7
LmjF.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmjF.16.0020 ⚠
adenylate kinase, putative
— OG7
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— OG7
LmjF.32.0720 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmjF.34.2790 ⚠
hypothetical protein, conserved
— OG7
LmjF.14.1270 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LmjF.26.1080 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.