LmjF.19.0660

DNA-directed RNA polymerases I and III subunit RPAC1, putative
Leishmania major strain Friedlin OG6: OG6_102180 OG7: OG7_0003550 109 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 109 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.31.2610 ⚠
RNA polymerase ii largest subunit
— +2 more Both
LmjF.30.1270 ⚠
hypothetical protein, conserved
— Both
LmjF.25.0620 ⚠
RNA polymerase I second largest subunit, puta
— OG7
LmjF.28.2060 ⚠
DNA-directed RNA polymerase-like protein
— Both
LmjF.27.1550 ⚠
DNA-directed RNA polymerase II-like protein
— OG7
LmjF.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— Both
LmjF.34.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— +2 more Both
LmjF.34.2790 ⚠
hypothetical protein, conserved
— Both
LmjF.31.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— Both
LmjF.16.1350 ⚠
DNA-directed rna polymerase I largest subunit
— +1 more Both
LmjF.09.1060 ⚠
DNA-directed RNA polymerase III subunit, puta
— OG7
LmjF.32.1400 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LmjF.23.1380 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LmjF.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.32.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.36.1360 ⚠
adenylate kinase, putative
— OG7
LmjF.04.0960 ⚠
UMP/CMP kinase, putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.16.0020 ⚠
adenylate kinase, putative
— OG7
LmjF.35.3500 ⚠
zinc finger protein, putative
— OG7
LmjF.35.4260 ⚠
predicted zinc finger protein
— OG7
LmjF.14.1170 ⚠
ras-like small GTPases, putative
— OG7
LmjF.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmjF.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmjF.14.0010 ⚠
exosome complex exonuclease, putative
— OG7
LmjF.24.1400 ⚠
hypothetical protein, conserved
— OG7
LmjF.13.1120 ⚠
DNA-directed RNA polymerase I subunit, putati
— OG7
LmjF.25.1315 ⚠
DNA-directed RNA polymerase I subunit RPB10,
— OG7
LmjF.12.0030 ⚠
proteasome beta-1 subunit, putative
— OG7
LmjF.35.3840 ⚠
proteasome beta 2 subunit, putative
— OG7
LmjF.21.0920 ⚠
histone H2A, putative
— OG7
LmjF.01.0560 ⚠
pre-mRNA processing factor 3 (PRP3)/Protein o
— OG7
LmjF.34.1170 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.0800 ⚠
ABC transport system ATP-binding protein, put
— OG7
LmjF.33.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LmjF.20.0490 ⚠
DNA-directed RNA polymerase 2, RPB12 subunit,
— OG7
LmjF.26.1140 ⚠
mitochondrial RNA binding complex 1 subunit,
— OG7
LmjF.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmjF.21.1330 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LmjF.35.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmjF.32.2910 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.35.2410 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.08.0090 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LmjF.09.0100 ⚠
flagellar pocket cytoskeletal protein bilbo1
— OG7
LmjF.32.1280 ⚠
RNA polymerase-like protein, putative
— OG7
LmjF.29.0400 ⚠
RNA polymerase Rpb4, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.