LmjF.01.0560

pre-mRNA processing factor 3 (PRP3)/Protein of unknown function (DUF1115), putative
Leishmania major strain Friedlin OG6: OG6_157627 OG7: OG7_0043643 60 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 60 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.36.0580 ⚠
hypothetical protein, unknown function
— OG7
LmjF.16.1250
hypothetical protein, conserved
— Both
LmjF.17.0300
hypothetical protein, conserved
— Both
LmjF.23.0650
spliceosomal U5 snRNP-specific protein, putat
— Both
LmjF.32.2200 ⚠
U5 small nuclear ribonucleoprotein component,
— Both
LmjF.16.1630
Putative snoRNA binding domain containing pro
— Both
LmjF.32.2490
hypothetical protein, conserved
— Both
LmjF.35.4460 ⚠
sm-f snRNP core complex protein, putative
— Both
LmjF.33.3190
small nuclear ribonucleoprotein SmD2
— Both
LmjF.35.3950
U5 snRNA-associated splicing factor
— Both
LmjF.26.0005 ⚠
Lsm7p protein, putative
— OG7
LmjF.01.0160 ⚠
LSM domain containing protein, putative
— OG7
LmjF.30.1205 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LmjF.28.2750 ⚠
receptor for activated C kinase 1
— OG7
LmjF.28.2740 ⚠
receptor for activated C kinase 1
— OG7
LmjF.25.1705 ⚠
LSM domain containing protein, putative
— Both
LmjF.30.1400 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.21.1566 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LmjF.36.0535 ⚠
U2 small nuclear ribonucleoprotein 16.5K, put
— OG7
LmjF.32.0715 ⚠
U6 snRNA-associated Sm-like protein LSm4p
— OG7
LmjF.35.4710 ⚠
170 kDa glucose-regulated protein, putative
— OG7
LmjF.26.0900 ⚠
heat shock 70 protein-like protein
— OG7
LmjF.01.0640 ⚠
HSP70-like protein
— OG7
LmjF.18.1370 ⚠
heat shock protein 110, putative
— OG7
LmjF.36.0190 ⚠
elongation factor 2
— OG7
LmjF.36.0180 ⚠
elongation factor 2
— OG7
LmjF.25.2080 ⚠
elongation factor 2-like protein
— OG7
LmjF.12.0030 ⚠
proteasome beta-1 subunit, putative
— OG7
LmjF.35.3840 ⚠
proteasome beta 2 subunit, putative
— OG7
LmjF.19.0660 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
LmjF.24.1400
hypothetical protein, conserved
— Both
LmjF.21.1120
U4/U6 small nuclear ribonuclear protein, puta
— OG6
LmjF.28.2960
U5 snRNP-specific 40 kDa protein, putative
— Both
LmjF.32.0680
OSM3-like kinesin, putative
— OG6
LmjF.30.0660
pdz domain containing protein, putative
— Both
LmjF.21.0530
hypothetical protein, conserved
— Both
LmjF.32.1470 ⚠
Microtubule-binding protein MIP-T3, putative
— Both
LmjF.26.0250
hypothetical protein, conserved
— Both
LmjF.09.1320
paraflagellar rod component, putative
— Both
LmjF.14.0010
exosome complex exonuclease, putative
— Both
LmjF.25.0715
hypothetical protein, conserved
— Both
LmjF.09.0100
flagellar pocket cytoskeletal protein bilbo1
— Both
LmjF.08.0090
adaptor complex protein (AP) 3 delta subunit
— Both
LmjF.29.0140 ⚠
DNA-directed RNA polymerase II subunit 3, put
— Both
LmjF.34.1170
hypothetical protein, conserved
— Both
LmjF.30.1270
hypothetical protein, conserved
— Both
LmjF.36.1650 ⚠
proteasome subunit beta type-5, putative
— Both
LmjF.34.2790
hypothetical protein, conserved
— Both
LmjF.22.1060
small nuclear ribonucleoprotein, putative
— Both
LmjF.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.