LmjF.30.1270

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_157001 OG7: OG7_0051147 82 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 82 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.29.0140 ⚠
DNA-directed RNA polymerase II subunit 3, put
— Both
LmjF.34.2790
hypothetical protein, conserved
— Both
LmjF.19.0660 ⚠
DNA-directed RNA polymerases I and III subuni
— Both
LmjF.23.1380 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LmjF.35.4260 ⚠
predicted zinc finger protein
— OG7
LmjF.32.1400 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.36.3160
tubulin binding cofactor c, putative
— OG7
LmjF.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmjF.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LmjF.33.1930 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmjF.34.4110
hypothetical protein, conserved
— Both
LmjF.36.2190
hypothetical protein, conserved
— Both
LmjF.36.5700
hypothetical protein, conserved
— Both
LmjF.36.2240
Gamma-tubulin complex component 3-like protei
— Both
LmjF.35.2250
hypothetical protein, conserved
— Both
LmjF.33.2070
mitogen-activated protein kinase, putative
— Both
LmjF.36.3960
hypothetical protein, unknown function
— Both
LmjF.33.1110
hypothetical protein, conserved
— Both
LmjF.34.3460
hypothetical protein, conserved
— Both
LmjF.35.2410 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.35.3840 ⚠
proteasome beta 2 subunit, putative
— OG7
LmjF.12.0030 ⚠
proteasome beta-1 subunit, putative
— OG7
LmjF.19.0800 ⚠
ABC transport system ATP-binding protein, put
— OG7
LmjF.33.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LmjF.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmjF.21.1330 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LmjF.35.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmjF.32.2910 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmjF.16.0020 ⚠
adenylate kinase, putative
— OG7
LmjF.04.0960 ⚠
UMP/CMP kinase, putative
— OG7
LmjF.36.1360 ⚠
adenylate kinase, putative
— OG7
LmjF.32.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmjF.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmjF.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmjF.14.1170 ⚠
ras-like small GTPases, putative
— OG7
LmjF.31.2970
acetyl-CoA carboxylase
— Both
LmjF.35.3500 ⚠
zinc finger protein, putative
— OG7
LmjF.10.0580
chromatin assembly factor 1 subunit A, putati
— Both
LmjF.08.0420
hypothetical protein, conserved
— Both
LmjF.22.1580 ⚠
exosome complex exonuclease RRP45 homolog, pu
— Both
LmjF.32.3460 ⚠
exosome-associated protein 2, putative
— Both
LmjF.10.0130
hypothetical protein, conserved
— Both
LmjF.26.1420 ⚠
FYVE zinc finger, putative
— Both
LmjF.11.1020
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.