LmjF.31.2970

acetyl-CoA carboxylase
Leishmania major strain Friedlin OG6: OG6_101052 OG7: OG7_0001434 192 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 192 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— +5 more Both
LmjF.08.0510 ⚠
ribose-phosphate pyrophosphokinase, putative
— +5 more Both
LmjF.33.1930 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +6 more Both
LmjF.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +6 more Both
LmjF.32.1400 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LmjF.23.1380 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LmjF.34.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— Both
LmjF.31.2610 ⚠
RNA polymerase ii largest subunit
— Both
LmjF.16.1350 ⚠
DNA-directed rna polymerase I largest subunit
— Both
LmjF.13.0500 ⚠
ATP-dependent RNA helicase, putative
— Both
LmjF.17.0920 ⚠
ATP-dependent RNA helicase, putative
— Both
LmjF.30.1270
hypothetical protein, conserved
— Both
LmjF.16.1220 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmjF.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmjF.36.2410 ⚠
Cullin protein neddylation domain containing
— OG7
LmjF.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmjF.36.3060 ⚠
cullin-like protein
— OG7
LmjF.35.3860 ⚠
T-complex protein 1, eta subunit, putative
— OG7
LmjF.13.1660 ⚠
chaperonin TCP20, putative
— OG7
LmjF.27.1260 ⚠
T-complex protein 1, beta subunit, putative
— OG7
LmjF.36.6910 ⚠
T-complex protein 1, theta subunit, putative
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.31.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmjF.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LmjF.05.0500 ⚠
ATP synthase F1, alpha subunit, putative
— Both
LmjF.05.0510 ⚠
ATP synthase F1, alpha subunit, putative
— Both
LmjF.30.3600
ATP synthase, epsilon chain, putative
— Both
LmjF.32.3930
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LmjF.29.0120
proteasome regulatory non-ATPase subunit, put
— Both
LmjF.34.0650
proteasome regulatory non-ATPase subunit 11,
— Both
LmjF.34.3080
exosome subunit rrp6p homologue, putative
— Both
LmjF.32.3270 ⚠
chaperonin alpha subunit, putative
— Both
LmjF.27.1460
proteasome regulatory non-ATP-ase subunit 3,
— Both
LmjF.12.0210
proteasome regulatory ATPase subunittcc1l8.3,
— OG6
LmjF.34.0350
eukaryotic translation initiation factor 5, p
— Both
LmjF.25.1280 ⚠
Cullin family/Cullin protein neddylation doma
— Both
LmjF.30.1090 ⚠
WW domain containing protein, putative
— Both
LmjF.23.0547
hypothetical protein, conserved
— Both
LmjF.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— Both
LmjF.15.0700
hypothetical protein, conserved
— Both
LmjF.07.1120
proteasome regulatory non-ATP-ase subunit, pu
— Both
LmjF.23.0120 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LmjF.31.1210
Protein of unknown function (DUF3638)/Protein
— Both
LmjF.27.0820
parallel beta-helix repeat, putative
— Both
LmjF.28.0110
proteasome beta 3 subunit, putative
— Both
LmjF.18.0820
hypothetical protein, conserved
— Both
LmjF.29.1900
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.