LmjF.31.1210

Protein of unknown function (DUF3638)/Protein of unknown function (DUF3645)/Zn-finger in Ran binding protein and others, putative
Leishmania major strain Friedlin OG6: OG6_111983 OG7: OG7_0009773 188 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 188 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.36.5240
glycosyl hydrolase, putative
— Both
LmjF.18.0820
hypothetical protein, conserved
— +2 more Both
LmjF.34.2240
Glycosyl hydrolase family 65 central catalyti
— Both
LmjF.23.1770
exosome component CSL4, putative
— Both
LmjF.36.3530 ⚠
polyubiquitin, putative
— OG7
LmjF.35.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmjF.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmjF.30.2280 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.32.2930 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.27.1780 ⚠
casein kinase I-like protein
— OG7
LmjF.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmjF.25.1580 ⚠
casein kinase I, putative
— OG7
LmjF.34.3020 ⚠
CK1/TTBK protein kinase, putative
— OG7
LmjF.35.1000 ⚠
casein kinase I, putative
— OG7
LmjF.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.04.1210 ⚠
casein kinase I, putative
— OG7
LmjF.30.3470 ⚠
casein kinase 1 isoform 2, putative
— OG7
LmjF.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmjF.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LmjF.33.1930 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmjF.17.0930 ⚠
formin, putative
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.11.0990 ⚠
adaptin-related protein-like protein
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.19.0420 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
LmjF.29.1830 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LmjF.14.1270 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LmjF.28.0120 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— OG7
LmjF.12.0300
hypothetical protein, conserved
— OG7
LmjF.19.0800 ⚠
ABC transport system ATP-binding protein, put
— OG7
LmjF.34.1000 ⚠
myosin IB heavy chain, putative
— OG7
LmjF.30.2540 ⚠
AAA family ATPase-like protein
— OG7
LmjF.27.1050 ⚠
vesicular transport protein (CDC48 homologue)
— OG7
LmjF.20.1530 ⚠
cell division cycle protein-like protein
— OG7
LmjF.27.0360 ⚠
ATPase, putative
— OG7
LmjF.34.3520 ⚠
peroxisome biosynthesis protein-like protein
— OG7
LmjF.16.0060 ⚠
peroxisome assembly protein, putative
— OG7
LmjF.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LmjF.31.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmjF.31.2650 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LmjF.09.0250 ⚠
DNA replication licensing factor MCM4, putati
— OG7
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmjF.06.0500 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.31.1900 ⚠
ubiquitin-fusion protein
— OG7
LmjF.31.2030 ⚠
ubiquitin-fusion protein
— OG7
LmjF.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmjF.34.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmjF.36.0600 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LmjF.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.36.6770 ⚠
beta adaptin, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.