LmjF.29.1830

dihydrolipoamide dehydrogenase, putative
Leishmania major strain Friedlin OG6: OG6_127035 OG7: OG7_0001633 115 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 115 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.31.2640 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— +1 more Both
LmjF.31.2650 ⚠
acetoin dehydrogenase e3 component-like prote
— +1 more Both
LmjF.25.0620 ⚠
RNA polymerase I second largest subunit, puta
— OG7
LmjF.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LmjF.31.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmjF.34.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmjF.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmjF.28.2385 ⚠
DNA replication licensing factor MCM6, putati
— OG7
LmjF.16.1220 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmjF.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmjF.31.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmjF.11.0260 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.1720 ⚠
neurobeachin/beige protein, putative
— OG7
LmjF.16.1350 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LmjF.33.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.34.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmjF.23.0120 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.25.0940 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.1630 ⚠
ccr4-not transcription complex subunit
— OG7
LmjF.16.0660 ⚠
hypothetical protein, conserved
— OG7
LmjF.11.0370 ⚠
hypothetical protein, conserved
— OG7
LmjF.25.1300 ⚠
PRP38 family, putative
— OG7
LmjF.24.2100 ⚠
hypothetical protein, conserved
— OG7
LmjF.18.0830 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
LmjF.16.0590 ⚠
carbamoyl-phosphate synthase, putative
— OG7
LmjF.29.1900 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.0250 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.04.0120 ⚠
exosome complex exonuclease RRP40, putative
— OG7
LmjF.18.0570 ⚠
hypothetical protein, conserved
— OG7
LmjF.25.1490 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
LmjF.36.2010 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.4090 ⚠
GRIP domain containing protein, putative
— OG7
LmjF.36.4210 ⚠
WD domain, G-beta repeat/Utp21 specific WD40
— OG7
LmjF.33.1880 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.14.1270 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LmjF.34.4110 ⚠
hypothetical protein, conserved
— OG7
LmjF.11.0990 ⚠
adaptin-related protein-like protein
— OG7
LmjF.32.2650 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.07.0550 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.0600 ⚠
hypothetical protein, conserved
— OG7
LmjF.14.0570 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.32.0140 ⚠
Flagellum attachment zone protein 9
— OG7
LmjF.09.0950 ⚠
O-phosphoseryl-tRNA(Sec) selenium transferase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.