LmjF.36.2010

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_157331 OG7: OG7_0063963 92 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 92 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.32.2930 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.28.2385 ⚠
DNA replication licensing factor MCM6, putati
— OG7
LmjF.32.2960 ⚠
DNA replication licensing factor MCM7, putati
— OG7
LmjF.33.2700 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LmjF.09.0250 ⚠
DNA replication licensing factor MCM4, putati
— OG7
LmjF.24.0910 ⚠
DNA replication licensing factor MCM5, putati
— OG7
LmjF.35.4910 ⚠
DNA replication licensing factor MCM9, putati
— OG7
LmjF.20.0790 ⚠
tubulin-tyrosine ligase, putative
— OG7
LmjF.29.0260 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LmjF.35.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmjF.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmjF.30.2280 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.05.0330 ⚠
DNA replication licensing factor MCM8, putati
— OG7
LmjF.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmjF.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.14.1270 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LmjF.36.3530 ⚠
polyubiquitin, putative
— OG7
LmjF.31.1900 ⚠
ubiquitin-fusion protein
— OG7
LmjF.31.2030 ⚠
ubiquitin-fusion protein
— OG7
LmjF.36.0600 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LmjF.17.0930 ⚠
formin, putative
— OG7
LmjF.31.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmjF.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LmjF.34.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmjF.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.06.0500 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.29.1830 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LmjF.31.2650 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LmjF.11.0990 ⚠
adaptin-related protein-like protein
— OG7
LmjF.36.6770 ⚠
beta adaptin, putative
— OG7
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmjF.28.1980
hypothetical protein, conserved
— Both
LmjF.34.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmjF.33.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.36.1720 ⚠
neurobeachin/beige protein, putative
— OG7
LmjF.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmjF.31.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmjF.16.1220 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmjF.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmjF.36.2410 ⚠
Cullin protein neddylation domain containing
— OG7
LmjF.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmjF.36.3060 ⚠
cullin-like protein
— OG7
LmjF.16.0660
hypothetical protein, conserved
— Both
LmjF.07.0380
RAVE protein 1 C terminal, putative
— Both
LmjF.32.2650 ⚠
SpoU rRNA Methylase family, putative
— Both
LmjF.18.0830
Periodic tryptophan protein 2 homolog, putati
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.