LmjF.13.0500

ATP-dependent RNA helicase, putative
Leishmania major strain Friedlin OG6: OG6_100305 OG7: OG7_0001850 141 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 141 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.35.3950 ⚠
U5 snRNA-associated splicing factor
— Both
LmjF.36.3060 ⚠
cullin-like protein
— OG7
LmjF.31.2970 ⚠
acetyl-CoA carboxylase
— Both
LmjF.16.1220 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmjF.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmjF.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmjF.25.1280 ⚠
Cullin family/Cullin protein neddylation doma
— Both
LmjF.36.2410 ⚠
Cullin protein neddylation domain containing
— OG7
LmjF.36.1360 ⚠
adenylate kinase, putative
— OG7
LmjF.36.5700 ⚠
hypothetical protein, conserved
— Both
LmjF.24.1060 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— Both
LmjF.32.0720 ⚠
hypothetical protein, conserved
— Both
LmjF.13.1070 ⚠
hypothetical protein, unknown function
— Both
LmjF.29.1900 ⚠
hypothetical protein, conserved
— Both
LmjF.21.1250 ⚠
adenylate kinase, putative
— Both
LmjF.13.1090 ⚠
proteasome regulatory ATPase subunit 2, putat
— OG6
LmjF.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— Both
LmjF.15.1190 ⚠
cyclic nucleotide-binding domain containing p
— Both
LmjF.02.0370 ⚠
proteasome regulatory non-ATPase subunit 6, p
— Both
LmjF.27.1460 ⚠
proteasome regulatory non-ATP-ase subunit 3,
— Both
LmjF.08.0510 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
LmjF.32.2200 ⚠
U5 small nuclear ribonucleoprotein component,
— Both
LmjF.36.4360 ⚠
19S proteasome regulatory subunit, Regulatory
— OG6
LmjF.32.3930 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LmjF.32.2130 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— Both
LmjF.33.0280 ⚠
hypothetical protein, conserved
— Both
LmjF.33.1930 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmjF.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LmjF.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmjF.21.1330 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LmjF.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.34.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmjF.32.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmjF.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmjF.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmjF.29.0140 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
LmjF.36.6770 ⚠
beta adaptin, putative
— OG7
LmjF.35.2410 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.35.4260 ⚠
predicted zinc finger protein
— OG7
LmjF.14.1170 ⚠
ras-like small GTPases, putative
— OG7
LmjF.36.1720 ⚠
neurobeachin/beige protein, putative
— OG7
LmjF.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmjF.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmjF.33.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.34.4620 ⚠
cyclic nucleotide-binding domain containing p
— OG7
LmjF.33.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LmjF.25.2080 ⚠
elongation factor 2-like protein
— OG7
LmjF.36.0180 ⚠
elongation factor 2
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.