LmjF.13.0680

Metallopeptidase family M24, putative
Leishmania major strain Friedlin OG6: OG6_146697 OG7: OG7_0006554 88 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 88 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.22.0530 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LmjF.22.1600 ⚠
ser/thr protein phosphatase, putative
— OG7
LmjF.17.0580 ⚠
bis(5'-nucleosyl)-tetraphosphatase, symmetric
— OG7
LmjF.01.0830 ⚠
metallo-peptidase, Clan MA(E), Family M3
— OG7
LmjF.02.0740 ⚠
dipeptylcarboxypeptidase, putative
— OG7
LmjF.27.2660 ⚠
peptidyl dipeptidase, putative
— OG7
LmjF.36.4450 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LmjF.26.1570 ⚠
thimet oligopeptidase, putative
— OG7
LmjF.33.2520 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— OG7
LmjF.35.0370 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
LmjF.01.0770 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LmjF.35.5210 ⚠
GTP-binding protein, putative
— OG7
LmjF.34.0150 ⚠
malate dehydrogenase, putative
— OG7
LmjF.21.1552 ⚠
ATP-dependent RNA helicase SUB2, putative
— OG7
LmjF.28.1530 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LmjF.01.0780 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LmjF.29.0300 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.0160 ⚠
mitochondrial malate dehydrogenase
— OG7
LmjF.36.6570 ⚠
y113g7b.23 protein-like protein
— OG7
LmjF.27.0720 ⚠
UBA/TS-N domain containing protein, putative
— OG7
LmjF.36.0540 ⚠
ubiquitin-like protein, putative
— OG7
LmjF.34.0130 ⚠
malate dehydrogenase, putative
— OG7
LmjF.32.1550 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.27.1460 ⚠
proteasome regulatory non-ATP-ase subunit 3,
— OG7
LmjF.15.0510 ⚠
ecotin, putative
— OG7
LmjF.15.0520 ⚠
ecotin, putative
— OG7
LmjF.15.0300 ⚠
Ecotin-like protein
— OG7
LmjF.11.0140 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LmjF.35.0950 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LmjF.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.26.1370 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LmjF.33.2400 ⚠
ras-like small GTPases, putative
— OG7
LmjF.18.0230 ⚠
60S ribosomal protein L7, putative
— OG7
LmjF.19.0710 ⚠
glycosomal malate dehydrogenase
— OG7
LmjF.05.0460 ⚠
GTPase, putative
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.36.7000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— OG7
LmjF.35.5000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmjF.29.1120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.13.0690 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.29.0270 ⚠
hypothetical protein, conserved
— Both
LmjF.29.2470 ⚠
60S ribosomal protein L13, putative
— Both
LmjF.34.2900 ⚠
ribosomal protein L3, putative
— Both
LmjF.36.5840 ⚠
hypothetical protein, conserved
— Both
LmjF.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— Both
LmjF.07.0510 ⚠
60S ribosomal protein L7a, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.